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Ester Hydrogenation with Bifunctional Metal–NHC Catalysts: Recent Advances
[Image: see text] Hydrogenation of ester to alcohol is an essential reaction in organic chemistry due to its importance in the production of a wide range of bulk and fine chemicals. There are a number of homogeneous and heterogeneous catalyst systems reported in the literature for this useful reacti...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7726748/ https://www.ncbi.nlm.nih.gov/pubmed/33324787 http://dx.doi.org/10.1021/acsomega.0c04819 |
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author | Pandey, Madhusudan K. Choudhury, Joyanta |
author_facet | Pandey, Madhusudan K. Choudhury, Joyanta |
author_sort | Pandey, Madhusudan K. |
collection | PubMed |
description | [Image: see text] Hydrogenation of ester to alcohol is an essential reaction in organic chemistry due to its importance in the production of a wide range of bulk and fine chemicals. There are a number of homogeneous and heterogeneous catalyst systems reported in the literature for this useful reaction. Mostly, phosphine-based bifunctional catalysts, owing to their ability to show metal–ligand cooperation during catalytic reactions, are extensively used in these reactions. However, phosphine-based catalysts are difficult to synthesize and are also highly air- and moisture-sensitive, restricting broad applications. In contrast, N-heterocyclic carbenes (NHCs) can be easily synthesized, and their steric and electronic attributes can be fine-tuned easily. In recent times, many phosphine ligands have been replaced by potent σ-donor NHCs, and the resulting bifunctional metal–ligand systems are proven to be very efficient in several important catalytic reactions. This mini-review focuses the recent advances mainly on bifunctional metal–NHC complexes utilized as (pre)catalysts in ester hydrogenation reactions. |
format | Online Article Text |
id | pubmed-7726748 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | American Chemical Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-77267482020-12-14 Ester Hydrogenation with Bifunctional Metal–NHC Catalysts: Recent Advances Pandey, Madhusudan K. Choudhury, Joyanta ACS Omega [Image: see text] Hydrogenation of ester to alcohol is an essential reaction in organic chemistry due to its importance in the production of a wide range of bulk and fine chemicals. There are a number of homogeneous and heterogeneous catalyst systems reported in the literature for this useful reaction. Mostly, phosphine-based bifunctional catalysts, owing to their ability to show metal–ligand cooperation during catalytic reactions, are extensively used in these reactions. However, phosphine-based catalysts are difficult to synthesize and are also highly air- and moisture-sensitive, restricting broad applications. In contrast, N-heterocyclic carbenes (NHCs) can be easily synthesized, and their steric and electronic attributes can be fine-tuned easily. In recent times, many phosphine ligands have been replaced by potent σ-donor NHCs, and the resulting bifunctional metal–ligand systems are proven to be very efficient in several important catalytic reactions. This mini-review focuses the recent advances mainly on bifunctional metal–NHC complexes utilized as (pre)catalysts in ester hydrogenation reactions. American Chemical Society 2020-11-23 /pmc/articles/PMC7726748/ /pubmed/33324787 http://dx.doi.org/10.1021/acsomega.0c04819 Text en © 2020 American Chemical Society This is an open access article published under an ACS AuthorChoice License (http://pubs.acs.org/page/policy/authorchoice_termsofuse.html) , which permits copying and redistribution of the article or any adaptations for non-commercial purposes. |
spellingShingle | Pandey, Madhusudan K. Choudhury, Joyanta Ester Hydrogenation with Bifunctional Metal–NHC Catalysts: Recent Advances |
title | Ester Hydrogenation with Bifunctional Metal–NHC Catalysts:
Recent Advances |
title_full | Ester Hydrogenation with Bifunctional Metal–NHC Catalysts:
Recent Advances |
title_fullStr | Ester Hydrogenation with Bifunctional Metal–NHC Catalysts:
Recent Advances |
title_full_unstemmed | Ester Hydrogenation with Bifunctional Metal–NHC Catalysts:
Recent Advances |
title_short | Ester Hydrogenation with Bifunctional Metal–NHC Catalysts:
Recent Advances |
title_sort | ester hydrogenation with bifunctional metal–nhc catalysts:
recent advances |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7726748/ https://www.ncbi.nlm.nih.gov/pubmed/33324787 http://dx.doi.org/10.1021/acsomega.0c04819 |
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