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Ester Hydrogenation with Bifunctional Metal–NHC Catalysts: Recent Advances

[Image: see text] Hydrogenation of ester to alcohol is an essential reaction in organic chemistry due to its importance in the production of a wide range of bulk and fine chemicals. There are a number of homogeneous and heterogeneous catalyst systems reported in the literature for this useful reacti...

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Autores principales: Pandey, Madhusudan K., Choudhury, Joyanta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7726748/
https://www.ncbi.nlm.nih.gov/pubmed/33324787
http://dx.doi.org/10.1021/acsomega.0c04819
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author Pandey, Madhusudan K.
Choudhury, Joyanta
author_facet Pandey, Madhusudan K.
Choudhury, Joyanta
author_sort Pandey, Madhusudan K.
collection PubMed
description [Image: see text] Hydrogenation of ester to alcohol is an essential reaction in organic chemistry due to its importance in the production of a wide range of bulk and fine chemicals. There are a number of homogeneous and heterogeneous catalyst systems reported in the literature for this useful reaction. Mostly, phosphine-based bifunctional catalysts, owing to their ability to show metal–ligand cooperation during catalytic reactions, are extensively used in these reactions. However, phosphine-based catalysts are difficult to synthesize and are also highly air- and moisture-sensitive, restricting broad applications. In contrast, N-heterocyclic carbenes (NHCs) can be easily synthesized, and their steric and electronic attributes can be fine-tuned easily. In recent times, many phosphine ligands have been replaced by potent σ-donor NHCs, and the resulting bifunctional metal–ligand systems are proven to be very efficient in several important catalytic reactions. This mini-review focuses the recent advances mainly on bifunctional metal–NHC complexes utilized as (pre)catalysts in ester hydrogenation reactions.
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spelling pubmed-77267482020-12-14 Ester Hydrogenation with Bifunctional Metal–NHC Catalysts: Recent Advances Pandey, Madhusudan K. Choudhury, Joyanta ACS Omega [Image: see text] Hydrogenation of ester to alcohol is an essential reaction in organic chemistry due to its importance in the production of a wide range of bulk and fine chemicals. There are a number of homogeneous and heterogeneous catalyst systems reported in the literature for this useful reaction. Mostly, phosphine-based bifunctional catalysts, owing to their ability to show metal–ligand cooperation during catalytic reactions, are extensively used in these reactions. However, phosphine-based catalysts are difficult to synthesize and are also highly air- and moisture-sensitive, restricting broad applications. In contrast, N-heterocyclic carbenes (NHCs) can be easily synthesized, and their steric and electronic attributes can be fine-tuned easily. In recent times, many phosphine ligands have been replaced by potent σ-donor NHCs, and the resulting bifunctional metal–ligand systems are proven to be very efficient in several important catalytic reactions. This mini-review focuses the recent advances mainly on bifunctional metal–NHC complexes utilized as (pre)catalysts in ester hydrogenation reactions. American Chemical Society 2020-11-23 /pmc/articles/PMC7726748/ /pubmed/33324787 http://dx.doi.org/10.1021/acsomega.0c04819 Text en © 2020 American Chemical Society This is an open access article published under an ACS AuthorChoice License (http://pubs.acs.org/page/policy/authorchoice_termsofuse.html) , which permits copying and redistribution of the article or any adaptations for non-commercial purposes.
spellingShingle Pandey, Madhusudan K.
Choudhury, Joyanta
Ester Hydrogenation with Bifunctional Metal–NHC Catalysts: Recent Advances
title Ester Hydrogenation with Bifunctional Metal–NHC Catalysts: Recent Advances
title_full Ester Hydrogenation with Bifunctional Metal–NHC Catalysts: Recent Advances
title_fullStr Ester Hydrogenation with Bifunctional Metal–NHC Catalysts: Recent Advances
title_full_unstemmed Ester Hydrogenation with Bifunctional Metal–NHC Catalysts: Recent Advances
title_short Ester Hydrogenation with Bifunctional Metal–NHC Catalysts: Recent Advances
title_sort ester hydrogenation with bifunctional metal–nhc catalysts: recent advances
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7726748/
https://www.ncbi.nlm.nih.gov/pubmed/33324787
http://dx.doi.org/10.1021/acsomega.0c04819
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