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Non‐apoptotic caspase activation preserves Drosophila intestinal progenitor cells in quiescence

Caspase malfunction in stem cells often precedes the appearance and progression of multiple types of cancer, including human colorectal cancer. However, the caspase‐dependent regulation of intestinal stem cell properties remains poorly understood. Here, we demonstrate that Dronc, the Drosophila orth...

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Detalles Bibliográficos
Autores principales: Arthurton, Lewis, Nahotko, Dominik Antoni, Alonso, Jana, Wendler, Franz, Baena‐Lopez, Luis Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7726796/
https://www.ncbi.nlm.nih.gov/pubmed/33135280
http://dx.doi.org/10.15252/embr.201948892