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Transcriptome Analysis Illuminates a Hub Role of SREBP2 in Cholesterol Metabolism by α-Mangostin

[Image: see text] Whole-transcriptome analysis of α-mangostin-treated HepG2 cells revealed that genes relevant to lipid and cholesterol metabolic processes responded to α-mangostin treatment. α-Mangostin downregulated a series of cholesterol biosynthetic genes, including SQLE, HMGCR, and LSS, and co...

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Detalles Bibliográficos
Autores principales:	Chae, Hee-Sung, Kim, Hyun Ji, Ko, Hyun-Jeong, Lee, Chang Hoon, Choi, Young Hee, Chin, Young-Won
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2020
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7726933/ https://www.ncbi.nlm.nih.gov/pubmed/33324821 http://dx.doi.org/10.1021/acsomega.0c04282

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