Switching the Regioselectivity Access to Pyrroles and Isoquinolines from Ketoxime Acetates and Ynals

[Image: see text] A novel formal [3+2] and [4+2] annulation of ketoxime acetates and ynals for the synthesis of pyrroles and isoquinolines has been developed. By simply switching the catalyst and solvent, the reaction proceeds via two pathways. The reactions are achieved under mild conditions with b...

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Autores principales: Liu, Tanggao, Xu, Fan, Liu, Xiaojuan, Huang, Zhiqing, Long, Lipeng, Xu, Guohai, Xiao, Hong, Chen, Zhengwang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7726942/
https://www.ncbi.nlm.nih.gov/pubmed/33324860
http://dx.doi.org/10.1021/acsomega.0c05272
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author Liu, Tanggao
Xu, Fan
Liu, Xiaojuan
Huang, Zhiqing
Long, Lipeng
Xu, Guohai
Xiao, Hong
Chen, Zhengwang
author_facet Liu, Tanggao
Xu, Fan
Liu, Xiaojuan
Huang, Zhiqing
Long, Lipeng
Xu, Guohai
Xiao, Hong
Chen, Zhengwang
author_sort Liu, Tanggao
collection PubMed
description [Image: see text] A novel formal [3+2] and [4+2] annulation of ketoxime acetates and ynals for the synthesis of pyrroles and isoquinolines has been developed. By simply switching the catalyst and solvent, the reaction proceeds via two pathways. The reactions are achieved under mild conditions with broad substrate scope and excellent regioselectivity.
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spelling pubmed-77269422020-12-14 Switching the Regioselectivity Access to Pyrroles and Isoquinolines from Ketoxime Acetates and Ynals Liu, Tanggao Xu, Fan Liu, Xiaojuan Huang, Zhiqing Long, Lipeng Xu, Guohai Xiao, Hong Chen, Zhengwang ACS Omega [Image: see text] A novel formal [3+2] and [4+2] annulation of ketoxime acetates and ynals for the synthesis of pyrroles and isoquinolines has been developed. By simply switching the catalyst and solvent, the reaction proceeds via two pathways. The reactions are achieved under mild conditions with broad substrate scope and excellent regioselectivity. American Chemical Society 2020-11-23 /pmc/articles/PMC7726942/ /pubmed/33324860 http://dx.doi.org/10.1021/acsomega.0c05272 Text en © 2020 The Authors. Published by American Chemical Society This is an open access article published under a Creative Commons Non-Commercial No Derivative Works (CC-BY-NC-ND) Attribution License (http://pubs.acs.org/page/policy/authorchoice_ccbyncnd_termsofuse.html) , which permits copying and redistribution of the article, and creation of adaptations, all for non-commercial purposes.
spellingShingle Liu, Tanggao
Xu, Fan
Liu, Xiaojuan
Huang, Zhiqing
Long, Lipeng
Xu, Guohai
Xiao, Hong
Chen, Zhengwang
Switching the Regioselectivity Access to Pyrroles and Isoquinolines from Ketoxime Acetates and Ynals
title Switching the Regioselectivity Access to Pyrroles and Isoquinolines from Ketoxime Acetates and Ynals
title_full Switching the Regioselectivity Access to Pyrroles and Isoquinolines from Ketoxime Acetates and Ynals
title_fullStr Switching the Regioselectivity Access to Pyrroles and Isoquinolines from Ketoxime Acetates and Ynals
title_full_unstemmed Switching the Regioselectivity Access to Pyrroles and Isoquinolines from Ketoxime Acetates and Ynals
title_short Switching the Regioselectivity Access to Pyrroles and Isoquinolines from Ketoxime Acetates and Ynals
title_sort switching the regioselectivity access to pyrroles and isoquinolines from ketoxime acetates and ynals
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7726942/
https://www.ncbi.nlm.nih.gov/pubmed/33324860
http://dx.doi.org/10.1021/acsomega.0c05272
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