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Dysregulation of Endothelial Nitric Oxide Synthase Does Not Depend on Hemodynamic Alterations in Bicuspid Aortic Valve Aortopathy

BACKGROUND: Bicuspid aortic valves (BAVs) predispose to ascending aortic aneurysm. Turbulent blood flow and genetic factors have been proposed as underlying mechanisms. Endothelial nitric oxide synthase (eNOS) has been implicated in BAV aortopathy, and its expression is regulated by wall shear stres...

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Detalles Bibliográficos
Autores principales:	Gauer, Simon, Balint, Brittany, Kollmann, Catherine, Federspiel, Jan M., Henn, Dominic, Bandner‐Risch, Doris, Schmied, Wolfram, Schäfers, Hans‐Joachim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7726972/ https://www.ncbi.nlm.nih.gov/pubmed/32873108 http://dx.doi.org/10.1161/JAHA.120.016471

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