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A systematic review of the association between fibromyalgia and functional gastrointestinal disorders

BACKGROUND: Fibromyalgia and functional gastrointestinal disorders (FGID) including irritable bowel syndrome (IBS) are common conditions presenting in clinical settings and are more prevalent in women. While the relationship between IBS and fibromyalgia has been demonstrated, a review of the prevale...

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Autores principales: Erdrich, Sharon, Hawrelak, Jason A., Myers, Stephen P., Harnett, Joanna E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7727037/
https://www.ncbi.nlm.nih.gov/pubmed/33343707
http://dx.doi.org/10.1177/1756284820977402
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author Erdrich, Sharon
Hawrelak, Jason A.
Myers, Stephen P.
Harnett, Joanna E.
author_facet Erdrich, Sharon
Hawrelak, Jason A.
Myers, Stephen P.
Harnett, Joanna E.
author_sort Erdrich, Sharon
collection PubMed
description BACKGROUND: Fibromyalgia and functional gastrointestinal disorders (FGID) including irritable bowel syndrome (IBS) are common conditions presenting in clinical settings and are more prevalent in women. While the relationship between IBS and fibromyalgia has been demonstrated, a review of the prevalence of the broader group of FGID in adults with fibromyalgia has not been undertaken. The aim of this review was to systematically review the published literature, identifying the comorbidity of FGID in people with fibromyalgia, and to discuss the clinical implications, limitations of current research and areas of interest for future research METHODS: Medline, Embase, CINAHL and Web of Science were searched during June 2019. Results were screened for original research articles meeting established criteria for identification of FGID in adults diagnosed with fibromyalgia. RESULTS: A total of 14 studies involving 1340 adults with fibromyalgia, 363 healthy controls and 441 adults with other pathologies were included in this review. Only 1 of the 14 studies included surveyed the full range of FGID . Functional gut disorders were matched to Rome II criteria for reporting and comparison. In addition to increased abdominal pain and functional bloating or gas, IBS of mixed-pattern and constipation-types appear to be more prevalent than diarrhoea-predominant IBS in adults with fibromyalgia. CONCLUSION: This review confirms previous reports that IBS is common in people living with fibromyalgia and suggests that IBS-mixed and constipation types predominate. An association with a range of FGID other than IBS is suggested, but data are limited. Research exploring the association between fibromyalgia and functional gastrointestinal dysfunction beyond IBS are warranted.
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spelling pubmed-77270372020-12-18 A systematic review of the association between fibromyalgia and functional gastrointestinal disorders Erdrich, Sharon Hawrelak, Jason A. Myers, Stephen P. Harnett, Joanna E. Therap Adv Gastroenterol Systematic Review BACKGROUND: Fibromyalgia and functional gastrointestinal disorders (FGID) including irritable bowel syndrome (IBS) are common conditions presenting in clinical settings and are more prevalent in women. While the relationship between IBS and fibromyalgia has been demonstrated, a review of the prevalence of the broader group of FGID in adults with fibromyalgia has not been undertaken. The aim of this review was to systematically review the published literature, identifying the comorbidity of FGID in people with fibromyalgia, and to discuss the clinical implications, limitations of current research and areas of interest for future research METHODS: Medline, Embase, CINAHL and Web of Science were searched during June 2019. Results were screened for original research articles meeting established criteria for identification of FGID in adults diagnosed with fibromyalgia. RESULTS: A total of 14 studies involving 1340 adults with fibromyalgia, 363 healthy controls and 441 adults with other pathologies were included in this review. Only 1 of the 14 studies included surveyed the full range of FGID . Functional gut disorders were matched to Rome II criteria for reporting and comparison. In addition to increased abdominal pain and functional bloating or gas, IBS of mixed-pattern and constipation-types appear to be more prevalent than diarrhoea-predominant IBS in adults with fibromyalgia. CONCLUSION: This review confirms previous reports that IBS is common in people living with fibromyalgia and suggests that IBS-mixed and constipation types predominate. An association with a range of FGID other than IBS is suggested, but data are limited. Research exploring the association between fibromyalgia and functional gastrointestinal dysfunction beyond IBS are warranted. SAGE Publications 2020-12-08 /pmc/articles/PMC7727037/ /pubmed/33343707 http://dx.doi.org/10.1177/1756284820977402 Text en © The Author(s), 2020 https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Systematic Review
Erdrich, Sharon
Hawrelak, Jason A.
Myers, Stephen P.
Harnett, Joanna E.
A systematic review of the association between fibromyalgia and functional gastrointestinal disorders
title A systematic review of the association between fibromyalgia and functional gastrointestinal disorders
title_full A systematic review of the association between fibromyalgia and functional gastrointestinal disorders
title_fullStr A systematic review of the association between fibromyalgia and functional gastrointestinal disorders
title_full_unstemmed A systematic review of the association between fibromyalgia and functional gastrointestinal disorders
title_short A systematic review of the association between fibromyalgia and functional gastrointestinal disorders
title_sort systematic review of the association between fibromyalgia and functional gastrointestinal disorders
topic Systematic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7727037/
https://www.ncbi.nlm.nih.gov/pubmed/33343707
http://dx.doi.org/10.1177/1756284820977402
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