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CTNNB1 Knockdown Inhibits Cell Proliferation and Aldosterone Secretion Through Inhibiting Wnt/β-Catenin Signaling in H295R Cells

Aldosterone-producing adenomas (APA) is one of the causative factors of primary aldosteronism. Previous studies have suggested that there are somatic CTNNB1 mutations in APA, but the specific mechanism of CTNNB1 mutation in APA tumorigenesis and aldosterone secretion remains unclear. In the present...

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Detalles Bibliográficos
Autores principales: Zhou, Tingting, Luo, Pengwei, Wang, Liang, Yang, Shiwei, Qin, Shiyuan, Wei, Zhitao, Liu, Jiwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7727057/
https://www.ncbi.nlm.nih.gov/pubmed/33287648
http://dx.doi.org/10.1177/1533033820979685

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