p53 upregulated by HIF-1α promotes hypoxia-induced G2/M arrest and renal fibrosis in vitro and in vivo

Hypoxia plays an important role in the genesis and progression of renal fibrosis. The underlying mechanisms, however, have not been sufficiently elucidated. We examined the role of p53 in hypoxia-induced renal fibrosis in cell culture (human and rat renal tubular epithelial cells) and a mouse unilat...

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Detalles Bibliográficos
Autores principales: Liu, Limin, Zhang, Peng, Bai, Ming, He, Lijie, Zhang, Lei, Liu, Ting, Yang, Zhen, Duan, Menglu, Liu, Minna, Liu, Baojian, Du, Rui, Qian, Qi, Sun, Shiren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7727266/
https://www.ncbi.nlm.nih.gov/pubmed/30032308
http://dx.doi.org/10.1093/jmcb/mjy042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7727266/
https://www.ncbi.nlm.nih.gov/pubmed/30032308
http://dx.doi.org/10.1093/jmcb/mjy042

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