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Inflammasomes within Hyperactive Murine Dendritic Cells Stimulate Long-Lived T Cell-Mediated Anti-tumor Immunity

Central to anti-tumor immunity are dendritic cells (DCs), which stimulate long-lived protective T cell responses. Recent studies have demonstrated that DCs can achieve a state of hyperactivation, which is associated with inflammasome activities within living cells. Herein, we report that hyperactive...

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Detalles Bibliográficos
Autores principales: Zhivaki, Dania, Borriello, Francesco, Chow, Ohn A., Doran, Benjamin, Fleming, Ira, Theisen, Derek J., Pallis, Paris, Shalek, Alex K., Sokol, Caroline L., Zanoni, Ivan, Kagan, Jonathan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7727444/
https://www.ncbi.nlm.nih.gov/pubmed/33207188
http://dx.doi.org/10.1016/j.celrep.2020.108381