First report of Mortierella wolfii causing fungal keratitis from a tertiary eye hospital in India

A young 33 year old male presented with non-resolving corneal infiltrate for 2 month duration in the right eye. KOH/ Calcoflour wet mount revealed sparsely septate fungal hyphae. Post therapeutic penetrating keratoplasty 3 doses of intracameral voriconazole(100μg/0.1ml) was administered suspecting r...

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Autores principales: Lily Therese, Kulandai, Lakshmipathy, Meena, Lakshmipathy, Dhanurekha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7727982/
https://www.ncbi.nlm.nih.gov/pubmed/32971689
http://dx.doi.org/10.4103/ijo.IJO_2136_19
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author Lily Therese, Kulandai
Lakshmipathy, Meena
Lakshmipathy, Dhanurekha
author_facet Lily Therese, Kulandai
Lakshmipathy, Meena
Lakshmipathy, Dhanurekha
author_sort Lily Therese, Kulandai
collection PubMed
description A young 33 year old male presented with non-resolving corneal infiltrate for 2 month duration in the right eye. KOH/ Calcoflour wet mount revealed sparsely septate fungal hyphae. Post therapeutic penetrating keratoplasty 3 doses of intracameral voriconazole(100μg/0.1ml) was administered suspecting recurrence. Fungal culture revealed non sporulating mould on SDA. PCR based DNA sequencing targeting the ITS region identified the fungal isolate as Mortierella wolfii (M. wolfii) belonging to zygomycetes. To the best of our knowledge, this is the first report of human fungal keratitis caused by M. wolfii.
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spelling pubmed-77279822020-12-11 First report of Mortierella wolfii causing fungal keratitis from a tertiary eye hospital in India Lily Therese, Kulandai Lakshmipathy, Meena Lakshmipathy, Dhanurekha Indian J Ophthalmol Case Reports A young 33 year old male presented with non-resolving corneal infiltrate for 2 month duration in the right eye. KOH/ Calcoflour wet mount revealed sparsely septate fungal hyphae. Post therapeutic penetrating keratoplasty 3 doses of intracameral voriconazole(100μg/0.1ml) was administered suspecting recurrence. Fungal culture revealed non sporulating mould on SDA. PCR based DNA sequencing targeting the ITS region identified the fungal isolate as Mortierella wolfii (M. wolfii) belonging to zygomycetes. To the best of our knowledge, this is the first report of human fungal keratitis caused by M. wolfii. Wolters Kluwer - Medknow 2020-10 2020-09-23 /pmc/articles/PMC7727982/ /pubmed/32971689 http://dx.doi.org/10.4103/ijo.IJO_2136_19 Text en Copyright: © 2020 Indian Journal of Ophthalmology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Reports
Lily Therese, Kulandai
Lakshmipathy, Meena
Lakshmipathy, Dhanurekha
First report of Mortierella wolfii causing fungal keratitis from a tertiary eye hospital in India
title First report of Mortierella wolfii causing fungal keratitis from a tertiary eye hospital in India
title_full First report of Mortierella wolfii causing fungal keratitis from a tertiary eye hospital in India
title_fullStr First report of Mortierella wolfii causing fungal keratitis from a tertiary eye hospital in India
title_full_unstemmed First report of Mortierella wolfii causing fungal keratitis from a tertiary eye hospital in India
title_short First report of Mortierella wolfii causing fungal keratitis from a tertiary eye hospital in India
title_sort first report of mortierella wolfii causing fungal keratitis from a tertiary eye hospital in india
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7727982/
https://www.ncbi.nlm.nih.gov/pubmed/32971689
http://dx.doi.org/10.4103/ijo.IJO_2136_19
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