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Large giant cell tumor of the posterior iliac bone – an atypical location. A case report and literature review

Giant cell tumor (GCT) is a locally aggressive tumor but with benignity features, representing approximately 18% of non-malignant bone tumors in European countries, with slight female predominance. Malignancy in GCT is rare, about <2% of cases and is more common at older ages. Is known that usual...

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Autores principales: Faur, Cosmin Ioan, Pop, Daniel Laurenţiu, Motoc, Andrei Gheorghe Marius, Folescu, Roxana, Grigoraş, Mirela Loredana, Gurguş, Daniela, Zamfir, Carmen Lăcrămioara, Iacob, Mihaela, Vermeşan, Dinu, Deleanu, Bogdan Nicolae, Hărăguş, Horia George, Maliţa, Daniel Claudiu, Abu-Awwad, Ahmed, Ghiga, Ion Lucian, Tudoran, Mariana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academy of Medical Sciences, Romanian Academy Publishing House, Bucharest 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7728104/
https://www.ncbi.nlm.nih.gov/pubmed/32747917
http://dx.doi.org/10.47162/RJME.61.1.28
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author Faur, Cosmin Ioan
Pop, Daniel Laurenţiu
Motoc, Andrei Gheorghe Marius
Folescu, Roxana
Grigoraş, Mirela Loredana
Gurguş, Daniela
Zamfir, Carmen Lăcrămioara
Iacob, Mihaela
Vermeşan, Dinu
Deleanu, Bogdan Nicolae
Hărăguş, Horia George
Maliţa, Daniel Claudiu
Abu-Awwad, Ahmed
Ghiga, Ion Lucian
Tudoran, Mariana
author_facet Faur, Cosmin Ioan
Pop, Daniel Laurenţiu
Motoc, Andrei Gheorghe Marius
Folescu, Roxana
Grigoraş, Mirela Loredana
Gurguş, Daniela
Zamfir, Carmen Lăcrămioara
Iacob, Mihaela
Vermeşan, Dinu
Deleanu, Bogdan Nicolae
Hărăguş, Horia George
Maliţa, Daniel Claudiu
Abu-Awwad, Ahmed
Ghiga, Ion Lucian
Tudoran, Mariana
author_sort Faur, Cosmin Ioan
collection PubMed
description Giant cell tumor (GCT) is a locally aggressive tumor but with benignity features, representing approximately 18% of non-malignant bone tumors in European countries, with slight female predominance. Malignancy in GCT is rare, about <2% of cases and is more common at older ages. Is known that usually occurs at the epiphyses of long bones, but extremely rare may have another location, such as the pelvic bone. An atypical location – the posterior iliac bone, found at a 34-year-old male –, is the case report we studied and described. Starting from the patient’s complains, like a mass in the left buttock region described as “recently appeared”, firm, not-mobile, with no distinctive borders and no tenderness at palpation, and a recent history trauma, multiple investigations have been performed, which have highlighted an osteolytic lesion, close to the sacroiliac joint, only with infiltration of the gluteal, iliac and paravertebral muscles. The treatment of choice was hemi-pelvectomy, with wide tumoral resection, and selective embolization of the nutrient vessels 24 hours prior to the surgical procedure. At two years postoperative, we found a good functional result and the computed tomography (CT) scan revealed no signs of recurrence.
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spelling pubmed-77281042020-12-18 Large giant cell tumor of the posterior iliac bone – an atypical location. A case report and literature review Faur, Cosmin Ioan Pop, Daniel Laurenţiu Motoc, Andrei Gheorghe Marius Folescu, Roxana Grigoraş, Mirela Loredana Gurguş, Daniela Zamfir, Carmen Lăcrămioara Iacob, Mihaela Vermeşan, Dinu Deleanu, Bogdan Nicolae Hărăguş, Horia George Maliţa, Daniel Claudiu Abu-Awwad, Ahmed Ghiga, Ion Lucian Tudoran, Mariana Rom J Morphol Embryol Case Report Giant cell tumor (GCT) is a locally aggressive tumor but with benignity features, representing approximately 18% of non-malignant bone tumors in European countries, with slight female predominance. Malignancy in GCT is rare, about <2% of cases and is more common at older ages. Is known that usually occurs at the epiphyses of long bones, but extremely rare may have another location, such as the pelvic bone. An atypical location – the posterior iliac bone, found at a 34-year-old male –, is the case report we studied and described. Starting from the patient’s complains, like a mass in the left buttock region described as “recently appeared”, firm, not-mobile, with no distinctive borders and no tenderness at palpation, and a recent history trauma, multiple investigations have been performed, which have highlighted an osteolytic lesion, close to the sacroiliac joint, only with infiltration of the gluteal, iliac and paravertebral muscles. The treatment of choice was hemi-pelvectomy, with wide tumoral resection, and selective embolization of the nutrient vessels 24 hours prior to the surgical procedure. At two years postoperative, we found a good functional result and the computed tomography (CT) scan revealed no signs of recurrence. Academy of Medical Sciences, Romanian Academy Publishing House, Bucharest 2020 2020-06-13 /pmc/articles/PMC7728104/ /pubmed/32747917 http://dx.doi.org/10.47162/RJME.61.1.28 Text en Copyright © 2020, Academy of Medical Sciences, Romanian Academy Publishing House, Bucharest http://creativecommons.org/licenses/by-nc-sa/4.0/ This is an open-access article distributed under the terms of a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International Public License, which permits unrestricted use, adaptation, distribution and reproduction in any medium, non-commercially, provided the new creations are licensed under identical terms as the original work and the original work is properly cited.
spellingShingle Case Report
Faur, Cosmin Ioan
Pop, Daniel Laurenţiu
Motoc, Andrei Gheorghe Marius
Folescu, Roxana
Grigoraş, Mirela Loredana
Gurguş, Daniela
Zamfir, Carmen Lăcrămioara
Iacob, Mihaela
Vermeşan, Dinu
Deleanu, Bogdan Nicolae
Hărăguş, Horia George
Maliţa, Daniel Claudiu
Abu-Awwad, Ahmed
Ghiga, Ion Lucian
Tudoran, Mariana
Large giant cell tumor of the posterior iliac bone – an atypical location. A case report and literature review
title Large giant cell tumor of the posterior iliac bone – an atypical location. A case report and literature review
title_full Large giant cell tumor of the posterior iliac bone – an atypical location. A case report and literature review
title_fullStr Large giant cell tumor of the posterior iliac bone – an atypical location. A case report and literature review
title_full_unstemmed Large giant cell tumor of the posterior iliac bone – an atypical location. A case report and literature review
title_short Large giant cell tumor of the posterior iliac bone – an atypical location. A case report and literature review
title_sort large giant cell tumor of the posterior iliac bone – an atypical location. a case report and literature review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7728104/
https://www.ncbi.nlm.nih.gov/pubmed/32747917
http://dx.doi.org/10.47162/RJME.61.1.28
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