Preparation of nanoliposomes containing HER2/neu (P5+435) peptide and evaluation of their immune responses and anti-tumoral effects as a prophylactic vaccine against breast cancer

HER2/neu is an immunogenic protein inducing both humoral and cell-mediated immune responses. The antigen-specific cytotoxic T lymphocytes (CTLs) are the main effector immune cells in the anti-tumor immunity. To induce an effective CTL specific response against P5+435 single peptide derived from rat...

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Detalles Bibliográficos
Autores principales: Naghibi, Laleh, Yazdani, Mona, Momtazi-Borojeni, Amir Abbas, Razazan, Atefeh, Shariat, Sheida, Mansourian, Mercedeh, Arab, Atefeh, Barati, Nastaran, Arabsalmani, Mahdieh, Abbasi, Azam, Saberi, Zahra, Badiee, Ali, Jalali, Seyed Amir, Jaafari, Mahmoud Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7728212/
https://www.ncbi.nlm.nih.gov/pubmed/33301467
http://dx.doi.org/10.1371/journal.pone.0243550

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