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Reduction of free polysaccharide contamination in the production of a 15-valent pneumococcal conjugate vaccine

Glycoconjugate vaccines are vaccines in which a bacterial polysaccharide antigen is conjugated to a carrier protein to enhance immunogenicity by promoting T cell-dependent immune response. However, the free (unreacted) polysaccharides remaining after the conjugation process can inhibit the immunogen...

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Detalles Bibliográficos
Autores principales:	Whang, Yoon Hee, Kim, Soo Kyung, Yoon, Hyeseon, Choi, Seuk Keun, Baik, Yeong Ok, Lee, Chankyu, Lee, Inhwan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7728214/ https://www.ncbi.nlm.nih.gov/pubmed/33301525 http://dx.doi.org/10.1371/journal.pone.0243909

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