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Structural intermediates in the low pH-induced transition of influenza hemagglutinin

The hemagglutinin (HA) glycoproteins of influenza viruses play a key role in binding host cell receptors and in mediating virus-host cell membrane fusion during virus infection. Upon virus entry, HA is triggered by low pH and undergoes large structural rearrangements from a prefusion state to a post...

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Detalles Bibliográficos
Autores principales: Gao, Jingjing, Gui, Miao, Xiang, Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7728236/
https://www.ncbi.nlm.nih.gov/pubmed/33253316
http://dx.doi.org/10.1371/journal.ppat.1009062