Vesicular trafficking permits evasion of cGAS/STING surveillance during initial human papillomavirus infection

Oncogenic human papillomaviruses (HPVs) replicate in differentiating epithelium, causing 5% of cancers worldwide. Like most other DNA viruses, HPV infection initiates after trafficking viral genome (vDNA) to host cell nuclei. Cells possess innate surveillance pathways to detect microbial components...

Descripción completa

Detalles Bibliográficos
Autores principales: Uhlorn, Brittany L., Jackson, Robert, Li, Shuaizhi, Bratton, Shauna M., Van Doorslaer, Koenraad, Campos, Samuel K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7728285/
https://www.ncbi.nlm.nih.gov/pubmed/33253291
http://dx.doi.org/10.1371/journal.ppat.1009028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7728285/
https://www.ncbi.nlm.nih.gov/pubmed/33253291
http://dx.doi.org/10.1371/journal.ppat.1009028

Ejemplares similares