Cargando…
Inhibiting the NLRP3 Inflammasome
Inflammasomes are protein complexes which are important in several inflammatory diseases. Inflammasomes form part of the innate immune system that triggers the activation of inflammatory cytokines interleukin (IL)-1β and IL-18. The inflammasome most studied in sterile inflammation and non-communicab...
Autores principales: | El-Sharkawy, Lina Y., Brough, David, Freeman, Sally |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7728307/ https://www.ncbi.nlm.nih.gov/pubmed/33255820 http://dx.doi.org/10.3390/molecules25235533 |
Ejemplares similares
-
LRRC8A is essential for hypotonicity-, but not for DAMP-induced NLRP3 inflammasome activation
por: Green, Jack P, et al.
Publicado: (2020) -
Design, Synthesis and Evaluation of Oxazaborine Inhibitors of the NLRP3 Inflammasome
por: Baldwin, Alex G., et al.
Publicado: (2018) -
The NLRP3–inflammasome as a sensor of organelle dysfunction
por: Seoane, Paula I., et al.
Publicado: (2020) -
Inhibition of the NLRP3 inflammasome by HSP90 inhibitors
por: Nizami, Sohaib, et al.
Publicado: (2020) -
Selective inhibition of the K(+) efflux sensitive NLRP3 pathway by Cl(−) channel modulation
por: Swanton, Tessa, et al.
Publicado: (2020)