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Modeling the pandemic trend of 2019 Coronavirus with optimal control analysis

In this work, we propose a mathematical model to analyze the outbreak of the Coronavirus disease (COVID-19). The proposed model portrays the multiple transmission pathways in the infection dynamics and stresses the role of the environmental reservoir in the transmission of the disease. The basic rep...

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Detalles Bibliográficos
Autores principales: Fatima, BiBi, Zaman, Gul, Alqudah, Manar A., Abdeljawad, Thabet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7728413/
https://www.ncbi.nlm.nih.gov/pubmed/33329991
http://dx.doi.org/10.1016/j.rinp.2020.103660
Descripción
Sumario:In this work, we propose a mathematical model to analyze the outbreak of the Coronavirus disease (COVID-19). The proposed model portrays the multiple transmission pathways in the infection dynamics and stresses the role of the environmental reservoir in the transmission of the disease. The basic reproduction number [Formula: see text] is calculated from the model to assess the transmissibility of the COVID-19. We discuss sensitivity analysis to clarify the importance of epidemic parameters. The stability theory is used to discuss the local as well as the global properties of the proposed model. The problem is formulated as an optimal control one to minimize the number of infected people and keep the intervention cost as low as possible. Medical mask, isolation, treatment, detergent spray will be involved in the model as time dependent control variables. Finally, we present and discuss results by using numerical simulations.