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Modeling the pandemic trend of 2019 Coronavirus with optimal control analysis
In this work, we propose a mathematical model to analyze the outbreak of the Coronavirus disease (COVID-19). The proposed model portrays the multiple transmission pathways in the infection dynamics and stresses the role of the environmental reservoir in the transmission of the disease. The basic rep...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Authors. Published by Elsevier B.V.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7728413/ https://www.ncbi.nlm.nih.gov/pubmed/33329991 http://dx.doi.org/10.1016/j.rinp.2020.103660 |
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author | Fatima, BiBi Zaman, Gul Alqudah, Manar A. Abdeljawad, Thabet |
author_facet | Fatima, BiBi Zaman, Gul Alqudah, Manar A. Abdeljawad, Thabet |
author_sort | Fatima, BiBi |
collection | PubMed |
description | In this work, we propose a mathematical model to analyze the outbreak of the Coronavirus disease (COVID-19). The proposed model portrays the multiple transmission pathways in the infection dynamics and stresses the role of the environmental reservoir in the transmission of the disease. The basic reproduction number [Formula: see text] is calculated from the model to assess the transmissibility of the COVID-19. We discuss sensitivity analysis to clarify the importance of epidemic parameters. The stability theory is used to discuss the local as well as the global properties of the proposed model. The problem is formulated as an optimal control one to minimize the number of infected people and keep the intervention cost as low as possible. Medical mask, isolation, treatment, detergent spray will be involved in the model as time dependent control variables. Finally, we present and discuss results by using numerical simulations. |
format | Online Article Text |
id | pubmed-7728413 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | The Authors. Published by Elsevier B.V. |
record_format | MEDLINE/PubMed |
spelling | pubmed-77284132020-12-11 Modeling the pandemic trend of 2019 Coronavirus with optimal control analysis Fatima, BiBi Zaman, Gul Alqudah, Manar A. Abdeljawad, Thabet Results Phys Article In this work, we propose a mathematical model to analyze the outbreak of the Coronavirus disease (COVID-19). The proposed model portrays the multiple transmission pathways in the infection dynamics and stresses the role of the environmental reservoir in the transmission of the disease. The basic reproduction number [Formula: see text] is calculated from the model to assess the transmissibility of the COVID-19. We discuss sensitivity analysis to clarify the importance of epidemic parameters. The stability theory is used to discuss the local as well as the global properties of the proposed model. The problem is formulated as an optimal control one to minimize the number of infected people and keep the intervention cost as low as possible. Medical mask, isolation, treatment, detergent spray will be involved in the model as time dependent control variables. Finally, we present and discuss results by using numerical simulations. The Authors. Published by Elsevier B.V. 2021-01 2020-12-09 /pmc/articles/PMC7728413/ /pubmed/33329991 http://dx.doi.org/10.1016/j.rinp.2020.103660 Text en © 2020 The Authors Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Fatima, BiBi Zaman, Gul Alqudah, Manar A. Abdeljawad, Thabet Modeling the pandemic trend of 2019 Coronavirus with optimal control analysis |
title | Modeling the pandemic trend of 2019 Coronavirus with optimal control analysis |
title_full | Modeling the pandemic trend of 2019 Coronavirus with optimal control analysis |
title_fullStr | Modeling the pandemic trend of 2019 Coronavirus with optimal control analysis |
title_full_unstemmed | Modeling the pandemic trend of 2019 Coronavirus with optimal control analysis |
title_short | Modeling the pandemic trend of 2019 Coronavirus with optimal control analysis |
title_sort | modeling the pandemic trend of 2019 coronavirus with optimal control analysis |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7728413/ https://www.ncbi.nlm.nih.gov/pubmed/33329991 http://dx.doi.org/10.1016/j.rinp.2020.103660 |
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