Sequential activation of transcriptional repressors promotes progenitor commitment by silencing stem cell identity genes

Stem cells that indirectly generate differentiated cells through intermediate progenitors drives vertebrate brain evolution. Due to a lack of lineage information, how stem cell functionality, including the competency to generate intermediate progenitors, becomes extinguished during progenitor commit...

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Detalles Bibliográficos
Autores principales: Rives-Quinto, Noemi, Komori, Hideyuki, Ostgaard, Cyrina M, Janssens, Derek H, Kondo, Shu, Dai, Qi, Moore, Adrian W, Lee, Cheng-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Stem Cells and Regenerative Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7728440/
https://www.ncbi.nlm.nih.gov/pubmed/33241994
http://dx.doi.org/10.7554/eLife.56187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7728440/
https://www.ncbi.nlm.nih.gov/pubmed/33241994
http://dx.doi.org/10.7554/eLife.56187

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