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Sequential activation of transcriptional repressors promotes progenitor commitment by silencing stem cell identity genes
Stem cells that indirectly generate differentiated cells through intermediate progenitors drives vertebrate brain evolution. Due to a lack of lineage information, how stem cell functionality, including the competency to generate intermediate progenitors, becomes extinguished during progenitor commit...
Autores principales: | Rives-Quinto, Noemi, Komori, Hideyuki, Ostgaard, Cyrina M, Janssens, Derek H, Kondo, Shu, Dai, Qi, Moore, Adrian W, Lee, Cheng-Yu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7728440/ https://www.ncbi.nlm.nih.gov/pubmed/33241994 http://dx.doi.org/10.7554/eLife.56187 |
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