High-resolution transcriptional and morphogenetic profiling of cells from micropatterned human ESC gastruloid cultures

During mammalian gastrulation, germ layers arise and are shaped into the body plan while extraembryonic layers sustain the embryo. Human embryonic stem cells, cultured with BMP4 on extracellular matrix micro-discs, reproducibly differentiate into gastruloids, expressing markers of germ layers and ex...

Descripción completa

Detalles Bibliográficos
Autores principales: Minn, Kyaw Thu, Fu, Yuheng C, He, Shenghua, Dietmann, Sabine, George, Steven C, Anastasio, Mark A, Morris, Samantha A, Solnica-Krezel, Lilianna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7728446/
https://www.ncbi.nlm.nih.gov/pubmed/33206048
http://dx.doi.org/10.7554/eLife.59445

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7728446/
https://www.ncbi.nlm.nih.gov/pubmed/33206048
http://dx.doi.org/10.7554/eLife.59445

Ejemplares similares