Tribbles-1 Expression and Its Function to Control Inflammatory Cytokines, Including Interleukin-8 Levels are Regulated by miRNAs in Macrophages and Prostate Cancer Cells

The pseudokinase TRIB1 controls cell function in a range of contexts, by regulating MAP kinase activation and mediating protein degradation via the COP1 ubiquitin ligase. TRIB1 regulates polarization of macrophages and dysregulated Trib1 expression in murine models has been shown to alter atheroscle...

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Detalles Bibliográficos
Autores principales: Niespolo, Chiara, Johnston, Jessica M., Deshmukh, Sumeet R., Satam, Swapna, Shologu, Ziyanda, Villacanas, Oscar, Sudbery, Ian M., Wilson, Heather L., Kiss-Toth, Endre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7728618/
https://www.ncbi.nlm.nih.gov/pubmed/33329538
http://dx.doi.org/10.3389/fimmu.2020.574046

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