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COVID-19 in Pediatric Patients: A Focus on CHD Patients

Coronavirus disease 2019 (COVID-19) is a global pandemic caused by SARS-CoV-2 virus. As of the 30th of September 2020, around 34,000,000 cases have been reported globally. Pediatrics with underlying congenital heart disease represent a small yet a critical proportion of these patients. In general, t...

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Autores principales: Zareef, Rana O., Younis, Nour K., Bitar, Fadi, Eid, Ali H., Arabi, Mariam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7728667/
https://www.ncbi.nlm.nih.gov/pubmed/33330675
http://dx.doi.org/10.3389/fcvm.2020.612460
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author Zareef, Rana O.
Younis, Nour K.
Bitar, Fadi
Eid, Ali H.
Arabi, Mariam
author_facet Zareef, Rana O.
Younis, Nour K.
Bitar, Fadi
Eid, Ali H.
Arabi, Mariam
author_sort Zareef, Rana O.
collection PubMed
description Coronavirus disease 2019 (COVID-19) is a global pandemic caused by SARS-CoV-2 virus. As of the 30th of September 2020, around 34,000,000 cases have been reported globally. Pediatrics with underlying congenital heart disease represent a small yet a critical proportion of these patients. In general, the majority of infected children experience mild to moderate disease with significant interindividual variability in laboratory and radiographic findings. Nevertheless, in healthy children with COVID-19, cardiac involvement has been documented and is attributed to various causes. Myocarditis, arrhythmias, cardiogenic shock, and serious multisystem inflammatory syndrome in children are all encountered. Since COVID-19 is a recent novel disease and based on previous experience with respiratory infections, children with underlying congenital heart disease should be given special attention. To date, little data is available about COVID-19 presentation, complications, and appropriate treatment in this population. However, variable and inconsistent disease presentation and severity have been observed. This paper discusses COVID-19 course of illness in pediatric population with a special emphasis on the cardiac manifestations of the disease in healthy population and also on the disease course in congenital heart disease patients in particular.
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spelling pubmed-77286672020-12-15 COVID-19 in Pediatric Patients: A Focus on CHD Patients Zareef, Rana O. Younis, Nour K. Bitar, Fadi Eid, Ali H. Arabi, Mariam Front Cardiovasc Med Cardiovascular Medicine Coronavirus disease 2019 (COVID-19) is a global pandemic caused by SARS-CoV-2 virus. As of the 30th of September 2020, around 34,000,000 cases have been reported globally. Pediatrics with underlying congenital heart disease represent a small yet a critical proportion of these patients. In general, the majority of infected children experience mild to moderate disease with significant interindividual variability in laboratory and radiographic findings. Nevertheless, in healthy children with COVID-19, cardiac involvement has been documented and is attributed to various causes. Myocarditis, arrhythmias, cardiogenic shock, and serious multisystem inflammatory syndrome in children are all encountered. Since COVID-19 is a recent novel disease and based on previous experience with respiratory infections, children with underlying congenital heart disease should be given special attention. To date, little data is available about COVID-19 presentation, complications, and appropriate treatment in this population. However, variable and inconsistent disease presentation and severity have been observed. This paper discusses COVID-19 course of illness in pediatric population with a special emphasis on the cardiac manifestations of the disease in healthy population and also on the disease course in congenital heart disease patients in particular. Frontiers Media S.A. 2020-11-27 /pmc/articles/PMC7728667/ /pubmed/33330675 http://dx.doi.org/10.3389/fcvm.2020.612460 Text en Copyright © 2020 Zareef, Younis, Bitar, Eid and Arabi. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cardiovascular Medicine
Zareef, Rana O.
Younis, Nour K.
Bitar, Fadi
Eid, Ali H.
Arabi, Mariam
COVID-19 in Pediatric Patients: A Focus on CHD Patients
title COVID-19 in Pediatric Patients: A Focus on CHD Patients
title_full COVID-19 in Pediatric Patients: A Focus on CHD Patients
title_fullStr COVID-19 in Pediatric Patients: A Focus on CHD Patients
title_full_unstemmed COVID-19 in Pediatric Patients: A Focus on CHD Patients
title_short COVID-19 in Pediatric Patients: A Focus on CHD Patients
title_sort covid-19 in pediatric patients: a focus on chd patients
topic Cardiovascular Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7728667/
https://www.ncbi.nlm.nih.gov/pubmed/33330675
http://dx.doi.org/10.3389/fcvm.2020.612460
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