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Xeroderma Pigmentosum C (XPC) Mutations in Primary Fibroblasts Impair Base Excision Repair Pathway and Increase Oxidative DNA Damage

Xeroderma Pigmentosum C (XPC) is a multi-functional protein that is involved not only in the repair of bulky lesions, post-irradiation, via nucleotide excision repair (NER) per se but also in oxidative DNA damage mending. Since base excision repair (BER) is the primary regulator of oxidative DNA dam...

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Detalles Bibliográficos
Autores principales:	Fayyad, Nour, Kobaisi, Farah, Beal, David, Mahfouf, Walid, Ged, Cécile, Morice-Picard, Fanny, Fayyad-Kazan, Mohammad, Fayyad-Kazan, Hussein, Badran, Bassam, Rezvani, Hamid R., Rachidi, Walid
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7728722/ https://www.ncbi.nlm.nih.gov/pubmed/33329698 http://dx.doi.org/10.3389/fgene.2020.561687

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