Long-term T cell fitness and proliferation is driven by AMPK-dependent regulation of reactive oxygen species

The AMP-activated kinase (AMPK) is a major energy sensor metabolic enzyme that is activated early during T cell immune responses but its role in the generation of effector T cells is still controversial. Using both in vitro and in vivo models of T cell proliferation, we show herein that AMPK is disp...

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Detalles Bibliográficos
Autores principales: Lepez, Anouk, Pirnay, Tiphène, Denanglaire, Sébastien, Perez-Morga, David, Vermeersch, Marjorie, Leo, Oberdan, Andris, Fabienne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7728748/
https://www.ncbi.nlm.nih.gov/pubmed/33303820
http://dx.doi.org/10.1038/s41598-020-78715-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7728748/
https://www.ncbi.nlm.nih.gov/pubmed/33303820
http://dx.doi.org/10.1038/s41598-020-78715-2

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