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Long-term T cell fitness and proliferation is driven by AMPK-dependent regulation of reactive oxygen species
The AMP-activated kinase (AMPK) is a major energy sensor metabolic enzyme that is activated early during T cell immune responses but its role in the generation of effector T cells is still controversial. Using both in vitro and in vivo models of T cell proliferation, we show herein that AMPK is disp...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7728748/ https://www.ncbi.nlm.nih.gov/pubmed/33303820 http://dx.doi.org/10.1038/s41598-020-78715-2 |