(R)-Roscovitine and CFTR modulators enhance killing of multi-drug resistant Burkholderia cenocepacia by cystic fibrosis macrophages

Cystic fibrosis (CF) is characterized by chronic bacterial infections and heightened inflammation. Widespread ineffective antibiotic use has led to increased isolation of drug resistant bacterial strains from respiratory samples. (R)-roscovitine (Seliciclib) is a unique drug that has many benefits i...

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Detalles Bibliográficos
Autores principales: Shrestha, Chandra L., Zhang, Shuzhong, Wisniewski, Benjamin, Häfner, Stephanie, Elie, Jonathan, Meijer, Laurent, Kopp, Benjamin T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7728753/
https://www.ncbi.nlm.nih.gov/pubmed/33303916
http://dx.doi.org/10.1038/s41598-020-78817-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7728753/
https://www.ncbi.nlm.nih.gov/pubmed/33303916
http://dx.doi.org/10.1038/s41598-020-78817-x

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