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Beta-hydroxybutyrate, an endogenous NLRP3 inflammasome inhibitor, attenuates anxiety-related behavior in a rodent post-traumatic stress disorder model
Accumulating evidence suggests that elevated inflammation contributes to the pathophysiology of post-traumatic stress disorder (PTSD) and that anti-inflammatory drugs might be a new treatment strategy for PTSD. It has been reported that beta-hydroxybutyrate (BHB), one of the main ketone bodies produ...
Autores principales: | Yamanashi, Takehiko, Iwata, Masaaki, Shibushita, Midori, Tsunetomi, Kyohei, Nagata, Mayu, Kajitani, Naofumi, Miura, Akihiko, Matsuo, Ryoichi, Nishiguchi, Tsuyoshi, Kato, Takahiro A., Setoyama, Daiki, Shirayama, Yukihiko, Watanabe, Ken, Shinozaki, Gen, Kaneko, Koichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7728809/ https://www.ncbi.nlm.nih.gov/pubmed/33303808 http://dx.doi.org/10.1038/s41598-020-78410-2 |
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