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Deep Learning on High-Throughput Transcriptomics to Predict Drug-Induced Liver Injury
Drug-induced liver injury (DILI) is one of the most cited reasons for the high drug attrition rate and drug withdrawal from the market. The accumulated large amount of high throughput transcriptomic profiles and advances in deep learning provide an unprecedented opportunity to improve the suboptimal...
Autores principales: | Li, Ting, Tong, Weida, Roberts, Ruth, Liu, Zhichao, Thakkar, Shraddha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7728858/ https://www.ncbi.nlm.nih.gov/pubmed/33330410 http://dx.doi.org/10.3389/fbioe.2020.562677 |
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