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Deep Learning on High-Throughput Transcriptomics to Predict Drug-Induced Liver Injury

Drug-induced liver injury (DILI) is one of the most cited reasons for the high drug attrition rate and drug withdrawal from the market. The accumulated large amount of high throughput transcriptomic profiles and advances in deep learning provide an unprecedented opportunity to improve the suboptimal...

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Detalles Bibliográficos
Autores principales: Li, Ting, Tong, Weida, Roberts, Ruth, Liu, Zhichao, Thakkar, Shraddha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7728858/
https://www.ncbi.nlm.nih.gov/pubmed/33330410
http://dx.doi.org/10.3389/fbioe.2020.562677

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