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Wrangling Shape-Shifting Morpheeins to Tackle Disease and Approach Drug Discovery
Homo-multimeric proteins that can come apart, change shape, and reassemble differently with functional consequences have been called morpheeins and/or transformers; these provide a largely unexplored context for understanding disease and developing allosteric therapeutics. This article describes suc...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7729013/ https://www.ncbi.nlm.nih.gov/pubmed/33330623 http://dx.doi.org/10.3389/fmolb.2020.582966 |