Cargando…
Total Flavonoids of Rhizoma Drynariae Enhances Angiogenic-Osteogenic Coupling During Distraction Osteogenesis by Promoting Type H Vessel Formation Through PDGF-BB/PDGFR-β Instead of HIF-1α/ VEGF Axis
Background: Total flavonoids of Rhizoma Drynariae (TFRD), extracted from the kidney-tonifying traditional Chinese medicine Rhizoma Rrynariae, has been proved to be effective in treating osteoporosis, bone fractures and defects. However, pharmacological effects of TFRD on type H vessels, angiogenic-o...
Autores principales: | Shen, Zhen, Chen, Zehua, Li, Zige, Zhang, Yan, Jiang, Tao, Lin, Haixiong, Huang, Minling, Chen, Huamei, Feng, Junjie, Jiang, Ziwei |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7729076/ https://www.ncbi.nlm.nih.gov/pubmed/33328980 http://dx.doi.org/10.3389/fphar.2020.503524 |
Ejemplares similares
-
Total flavonoids of Rhizoma Drynariae enhances CD31(hi)Emcn(hi) vessel formation and subsequent bone regeneration in rat models of distraction osteogenesis by activating PDGF-BB/VEGF/RUNX2/OSX signaling axis
por: Shen, Zhen, et al.
Publicado: (2022) -
PDGFR in PDGF-BB/PDGFR Signaling Pathway Does Orchestrates Osteogenesis in a Temporal Manner
por: Wang, Fangqian, et al.
Publicado: (2023) -
Identified the Synergistic Mechanism of Drynariae Rhizoma for Treating Fracture Based on Network Pharmacology
por: Lin, Haixiong, et al.
Publicado: (2019) -
Exploring the Mechanism of Total Flavonoids of Drynariae Rhizoma to Improve Large Bone Defects by Network Pharmacology and Experimental Assessment
por: Sun, Weipeng, et al.
Publicado: (2021) -
The effects of Rhizoma Curculiginis and Rhizoma Drynariae extracts on bones
por: Wong, Ricky WK, et al.
Publicado: (2007)