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Bone marrow mesenchymal stem cell transplantation downregulates plasma level and the microglia expression of transforming growth factor β1 in the acute phase of cerebral cortex ischemia

BACKGROUND: Both bone marrow mesenchymal stem cell (BM-MSC) and transforming growth factor-β1 (TGF-β1) have a strong anti-inflammatory capacity in stroke. But their relationship has not been well addressed. In this study, we investigated how intravenous BM-MSC transplantation in rats effected the ex...

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Detalles Bibliográficos
Autores principales: Liang, Zhao-Hui, Gu, Jian-Juan, Yu, Wen-Xiu, Guan, Yun-Qian, Khater, Mostafa, Li, Xiao-Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Medical Association 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7729118/
https://www.ncbi.nlm.nih.gov/pubmed/33336172
http://dx.doi.org/10.1016/j.cdtm.2020.05.005