A Hydrogel-Based Ultrasonic Backscattering Wireless Biochemical Sensing

Wireless monitoring of the physio-biochemical information is becoming increasingly important for healthcare. In this work, we present a proof-of-concept hydrogel-based wireless biochemical sensing scheme utilizing ultrasound. The sensing system utilizes silica-nanoparticle embedded hydrogel deposite...

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Autores principales: Nam, Juhong, Byun, Eunjeong, Shim, Hyunji, Kim, Esther, Islam, Sayemul, Park, Moonchul, Kim, Albert, Song, Seung Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7729131/
https://www.ncbi.nlm.nih.gov/pubmed/33330426
http://dx.doi.org/10.3389/fbioe.2020.596370
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author Nam, Juhong
Byun, Eunjeong
Shim, Hyunji
Kim, Esther
Islam, Sayemul
Park, Moonchul
Kim, Albert
Song, Seung Hyun
author_facet Nam, Juhong
Byun, Eunjeong
Shim, Hyunji
Kim, Esther
Islam, Sayemul
Park, Moonchul
Kim, Albert
Song, Seung Hyun
author_sort Nam, Juhong
collection PubMed
description Wireless monitoring of the physio-biochemical information is becoming increasingly important for healthcare. In this work, we present a proof-of-concept hydrogel-based wireless biochemical sensing scheme utilizing ultrasound. The sensing system utilizes silica-nanoparticle embedded hydrogel deposited on a thin glass substrate, which presents two prominent interfaces for ultrasonic backscattering (tissue/glass and hydrogel/glass). To overcome the effect of the varying acoustic properties of the intervening biological tissues between the sensor and the external transducer, we implemented a differential mode of ultrasonic back-scattering. Here, we demonstrate a wireless pH measurement with a resolution of 0.2 pH level change and a wireless sensing range around 10 cm in a water tank.
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spelling pubmed-77291312020-12-15 A Hydrogel-Based Ultrasonic Backscattering Wireless Biochemical Sensing Nam, Juhong Byun, Eunjeong Shim, Hyunji Kim, Esther Islam, Sayemul Park, Moonchul Kim, Albert Song, Seung Hyun Front Bioeng Biotechnol Bioengineering and Biotechnology Wireless monitoring of the physio-biochemical information is becoming increasingly important for healthcare. In this work, we present a proof-of-concept hydrogel-based wireless biochemical sensing scheme utilizing ultrasound. The sensing system utilizes silica-nanoparticle embedded hydrogel deposited on a thin glass substrate, which presents two prominent interfaces for ultrasonic backscattering (tissue/glass and hydrogel/glass). To overcome the effect of the varying acoustic properties of the intervening biological tissues between the sensor and the external transducer, we implemented a differential mode of ultrasonic back-scattering. Here, we demonstrate a wireless pH measurement with a resolution of 0.2 pH level change and a wireless sensing range around 10 cm in a water tank. Frontiers Media S.A. 2020-11-27 /pmc/articles/PMC7729131/ /pubmed/33330426 http://dx.doi.org/10.3389/fbioe.2020.596370 Text en Copyright © 2020 Nam, Byun, Shim, Kim, Islam, Park, Kim and Song. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Bioengineering and Biotechnology
Nam, Juhong
Byun, Eunjeong
Shim, Hyunji
Kim, Esther
Islam, Sayemul
Park, Moonchul
Kim, Albert
Song, Seung Hyun
A Hydrogel-Based Ultrasonic Backscattering Wireless Biochemical Sensing
title A Hydrogel-Based Ultrasonic Backscattering Wireless Biochemical Sensing
title_full A Hydrogel-Based Ultrasonic Backscattering Wireless Biochemical Sensing
title_fullStr A Hydrogel-Based Ultrasonic Backscattering Wireless Biochemical Sensing
title_full_unstemmed A Hydrogel-Based Ultrasonic Backscattering Wireless Biochemical Sensing
title_short A Hydrogel-Based Ultrasonic Backscattering Wireless Biochemical Sensing
title_sort hydrogel-based ultrasonic backscattering wireless biochemical sensing
topic Bioengineering and Biotechnology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7729131/
https://www.ncbi.nlm.nih.gov/pubmed/33330426
http://dx.doi.org/10.3389/fbioe.2020.596370
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