A pilot protocol to assess the feasibility of a virtual multiple crossover, randomized controlled trial design using methylphenidate in mild cognitive impairment

BACKGROUND: The conventional clinical trial design in Alzheimer’s disease (AD) and AD-related disorders (ADRDs) is the parallel-group randomized controlled trial. However, in heterogeneous disorders like AD/ADRDs, this design requires large sample sizes to detect meaningful effects in an “average” p...

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Detalles Bibliográficos
Autores principales: DesRuisseaux, Libby A., Williams, Victoria J., McManus, Alison J., Gupta, Anoopum S., Carlyle, Becky C., Azami, Hamed, Gerber, Jessica A., Bolling, Anna M., Cook, Carolyn L., Betensky, Rebecca A., Arnold, Steven E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7729136/
https://www.ncbi.nlm.nih.gov/pubmed/33308285
http://dx.doi.org/10.1186/s13063-020-04752-x

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