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Transcriptome Reprogramming of CD11b(+) Bone Marrow Cells by Pancreatic Cancer Extracellular Vesicles

Pancreatic cancers (PC) are highly metastatic with poor prognosis, mainly due to delayed detection. We previously showed that PC-derived extracellular vesicles (EVs) act on macrophages residing in the liver, eliciting extracellular matrix remodeling in this organ and marked hepatic accumulation of C...

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Detalles Bibliográficos
Autores principales: Maia, Joana, Otake, Andreia Hanada, Poças, Juliana, Carvalho, Ana Sofia, Beck, Hans Christian, Magalhães, Ana, Matthiesen, Rune, Strano Moraes, Maria Carolina, Costa-Silva, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7729189/
https://www.ncbi.nlm.nih.gov/pubmed/33330473
http://dx.doi.org/10.3389/fcell.2020.592518