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Appropriate extent of surgery for aspirin-exacerbated respiratory disease

The current literature lacks strong guidelines regarding surgical management of patients with aspirin-exacerbated respiratory disease (AERD), who present with the clinical triad of chronic rhinosinusitis with nasal polyposis (CRSwNP), bronchial asthma, and aspirin/nonsteroidal anti-inflammatory drug...

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Detalles Bibliográficos
Autores principales: Muhonen, Ethan G., Goshtasbi, Khodayar, Papagiannopoulos, Peter, Kuan, Edward C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7729211/
https://www.ncbi.nlm.nih.gov/pubmed/33336179
http://dx.doi.org/10.1016/j.wjorl.2020.07.005
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author Muhonen, Ethan G.
Goshtasbi, Khodayar
Papagiannopoulos, Peter
Kuan, Edward C.
author_facet Muhonen, Ethan G.
Goshtasbi, Khodayar
Papagiannopoulos, Peter
Kuan, Edward C.
author_sort Muhonen, Ethan G.
collection PubMed
description The current literature lacks strong guidelines regarding surgical management of patients with aspirin-exacerbated respiratory disease (AERD), who present with the clinical triad of chronic rhinosinusitis with nasal polyposis (CRSwNP), bronchial asthma, and aspirin/nonsteroidal anti-inflammatory drug intolerance. To further define the effectiveness of sinus surgery in treating AERD patients, this review article discusses current evidence regarding outcomes associated with more extensive surgery, the benefits of frontal sinus surgery on polyposis, and the role of Draf III intervention. Numerous studies suggest that Draf III frontal sinusotomy may be an efficacious early intervention due to increased neo-ostial patency and subsequent distribution of topical therapies. Future studies that further investigate the efficacy and safety of extensive surgery in AERD patients are warranted.
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spelling pubmed-77292112020-12-16 Appropriate extent of surgery for aspirin-exacerbated respiratory disease Muhonen, Ethan G. Goshtasbi, Khodayar Papagiannopoulos, Peter Kuan, Edward C. World J Otorhinolaryngol Head Neck Surg Review Article The current literature lacks strong guidelines regarding surgical management of patients with aspirin-exacerbated respiratory disease (AERD), who present with the clinical triad of chronic rhinosinusitis with nasal polyposis (CRSwNP), bronchial asthma, and aspirin/nonsteroidal anti-inflammatory drug intolerance. To further define the effectiveness of sinus surgery in treating AERD patients, this review article discusses current evidence regarding outcomes associated with more extensive surgery, the benefits of frontal sinus surgery on polyposis, and the role of Draf III intervention. Numerous studies suggest that Draf III frontal sinusotomy may be an efficacious early intervention due to increased neo-ostial patency and subsequent distribution of topical therapies. Future studies that further investigate the efficacy and safety of extensive surgery in AERD patients are warranted. KeAi Publishing 2020-09-08 /pmc/articles/PMC7729211/ /pubmed/33336179 http://dx.doi.org/10.1016/j.wjorl.2020.07.005 Text en © 2020 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review Article
Muhonen, Ethan G.
Goshtasbi, Khodayar
Papagiannopoulos, Peter
Kuan, Edward C.
Appropriate extent of surgery for aspirin-exacerbated respiratory disease
title Appropriate extent of surgery for aspirin-exacerbated respiratory disease
title_full Appropriate extent of surgery for aspirin-exacerbated respiratory disease
title_fullStr Appropriate extent of surgery for aspirin-exacerbated respiratory disease
title_full_unstemmed Appropriate extent of surgery for aspirin-exacerbated respiratory disease
title_short Appropriate extent of surgery for aspirin-exacerbated respiratory disease
title_sort appropriate extent of surgery for aspirin-exacerbated respiratory disease
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7729211/
https://www.ncbi.nlm.nih.gov/pubmed/33336179
http://dx.doi.org/10.1016/j.wjorl.2020.07.005
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