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Sodium–Taste Cells Require Skn-1a for Generation and Share Molecular Features with Sweet, Umami, and Bitter Taste Cells
Taste buds are maintained via continuous turnover of taste bud cells derived from local epithelial stem cells. A transcription factor Skn-1a (also known as Pou2f3) is required for the generation of sweet, umami (savory), and bitter taste cells that commonly express TRPM5 and CALHM ion channels. Here...
Autores principales: | Ohmoto, Makoto, Jyotaki, Masafumi, Foskett, J. Kevin, Matsumoto, Ichiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7729297/ https://www.ncbi.nlm.nih.gov/pubmed/33219051 http://dx.doi.org/10.1523/ENEURO.0385-20.2020 |
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