Remifentanil repairs cartilage damage and reduces the degradation of cartilage matrix in post-traumatic osteoarthritis, and inhibits IL-1β-induced apoptosis of articular chondrocytes via inhibition of PI3K/AKT/NF-κB phosphorylation

BACKGROUND: Remifentanil (RFT) is an opioid analgesic with a unique pharmacokinetic profile, and plays an important role in the intra- and post-operative periods. Post-traumatic osteoarthritis (PTO) is a particular type of osteoarthritis (OA) that occurs secondary to a traumatic injury. In the prese...

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Detalles Bibliográficos
Autores principales: Ke, Hai, Mou, Xiaping, Xia, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7729373/
https://www.ncbi.nlm.nih.gov/pubmed/33313232
http://dx.doi.org/10.21037/atm-20-6000

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7729373/
https://www.ncbi.nlm.nih.gov/pubmed/33313232
http://dx.doi.org/10.21037/atm-20-6000

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