Cargando…

Delivery of vascular endothelial growth factor (VEGFC) via engineered exosomes improves lymphedema

BACKGROUND: Lymphedema is a chronic disease results from impaired flow of the lymphatic system. Therefore, reconstruction of lymphatic system is crucial to treat limb lymphedema. Vascular endothelial growth factor (VEGFC) has been reported to be an important regulator involved in the growth and diff...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Bohan, Yang, Jiantao, Wang, Raoping, Li, Jia, Li, Xubo, Zhou, Xiang, Qiu, Shuai, Weng, Ricong, Wu, Zichao, Tang, Chunyuan, Li, Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7729376/ https://www.ncbi.nlm.nih.gov/pubmed/33313243 http://dx.doi.org/10.21037/atm-20-6605

Ejemplares similares

Erratum to delivery of vascular endothelial growth factor (VEGFC) via engineered exosomes improves lymphedema
Publicado: (2021)

Nucleoside-modified VEGFC mRNA induces organ-specific lymphatic growth and reverses experimental lymphedema
por: Szőke, Dániel, et al.
Publicado: (2021)

Genomic Landscapes of Noncoding RNAs Regulating VEGFA and VEGFC Expression in Endothelial Cells
por: Mushimiyimana, Isidore, et al.
Publicado: (2021)

Emerging Role of VEGFC in Pathological Angiogenesis
por: Nagai, Nao, et al.
Publicado: (2015)

The Relationship between VEGFC Gene Polymorphisms and Autoimmune Thyroiditis
por: Gao, Chaoqun, et al.
Publicado: (2022)

Metallothionein 2 regulates endothelial cell migration through transcriptional regulation of vegfc expression
por: Schuermann, Annika, et al.
Publicado: (2015)

Engineering exosomes for targeted drug delivery
por: Liang, Yujie, et al.
Publicado: (2021)

Can VEGFC Form Turing Patterns in the Zebrafish Embryo?
por: Wertheim, Kenneth Y., et al.
Publicado: (2019)

VEGFC negatively regulates the growth and aggressiveness of medulloblastoma cells
por: Penco-Campillo, Manon, et al.
Publicado: (2020)

Macrophage efferocytosis with VEGFC and lymphangiogenesis: rescuing the broken heart
por: D’Amore, Patricia A., et al.
Publicado: (2022)

Circular RNA circVEGFC accelerates high glucose-induced vascular endothelial cells apoptosis through miR-338-3p/HIF-1α/VEGFA axis
por: Wei, Hua, et al.
Publicado: (2020)

VEGFC/FLT4-induced cell-cycle arrest mediates sprouting and differentiation of venous and lymphatic endothelial cells
por: Jerafi-Vider, Ayelet, et al.
Publicado: (2021)

A Novel Role of VEGFC in Cerebral Ischemia With Lung Injury
por: Wen, Mu-Dong, et al.
Publicado: (2019)

Coordinating Effect of VEGFC and Oleic Acid Participates to Tumor Lymphangiogenesis
por: Morfoisse, Florent, et al.
Publicado: (2021)

HHEX is a transcriptional regulator of the VEGFC/FLT4/PROX1 signaling axis during vascular development
por: Gauvrit, Sébastien, et al.
Publicado: (2018)

Clinical importance of VEGFC and PD‐L1 co‐expression in lung adenocarcinoma patients
por: Qin, Tingting, et al.
Publicado: (2020)

BRG1 targeting STAT3/VEGFC signaling regulates lymphangiogenesis in colorectal cancer
por: Zhu, Xu, et al.
Publicado: (2016)

c‐Myc promotes lymphatic metastasis of pancreatic neuroendocrine tumor through VEGFC upregulation
por: Chang, Tsung‐Ming, et al.
Publicado: (2020)

Engineering blood exosomes for tumor-targeting efficient gene/chemo combination therapy
por: Zhan, Qi, et al.
Publicado: (2020)

Prediction of prognosis and immunotherapy response in lung adenocarcinoma based on CD79A, DKK1 and VEGFC
por: Zhang, Qilong, et al.
Publicado: (2023)

BACH family members regulate angiogenesis and lymphangiogenesis by modulating VEGFC expression
por: Cohen, Batya, et al.
Publicado: (2020)

Author Correction: VEGFC negatively regulates the growth and aggressiveness of medulloblastoma cells
por: Penco-Campillo, Manon, et al.
Publicado: (2020)

Macrophage-produced VEGFC is induced by efferocytosis to ameliorate cardiac injury and inflammation
por: Glinton, Kristofor E., et al.
Publicado: (2022)

Subconjunctival Lymphatics Respond to VEGFC and Anti-Metabolites in Rabbit and Mouse Eyes
por: Lee, Jong Yeon, et al.
Publicado: (2022)

Fenofibrate inhibits the expression of VEGFC and VEGFR-3 in retinal pigmental epithelial cells exposed to hypoxia
por: ZHAO, JIANFENG, et al.
Publicado: (2015)

Poor sleep and reduced quality of life were associated with symptom distress in patients receiving maintenance hemodialysis
por: Wang, Raoping, et al.
Publicado: (2016)

VEGFC acts as a double-edged sword in renal cell carcinoma aggressiveness
por: Ndiaye, Papa Diogop, et al.
Publicado: (2019)

CircRNA circVEGFC is Highly Expressed in Gestational Diabetes Mellitus (GDM) and It is Correlated with Multiple Adverse Events
por: She, Wenjing, et al.
Publicado: (2021)

Exosomes in the Regulation of Vascular Endothelial Cell Regeneration
por: Baruah, Jugajyoti, et al.
Publicado: (2020)

ZKSCAN5 Activates VEGFC Expression by Recruiting SETD7 to Promote the Lymphangiogenesis, Tumour Growth, and Metastasis of Breast Cancer
por: Li, Jingtong, et al.
Publicado: (2022)

Biodistribution of Exosomes and Engineering Strategies for Targeted Delivery of Therapeutic Exosomes
por: Choi, Hojun, et al.
Publicado: (2021)

Endothelial glycocalyx in hepatopulmonary syndrome: An indispensable player mediating vascular changes
por: Li, Liang, et al.
Publicado: (2022)

Engineering strategies and optimized delivery of exosomes for theranostic application in nerve tissue
por: Li, Qicheng, et al.
Publicado: (2023)

mafba is a downstream transcriptional effector of Vegfc signaling essential for embryonic lymphangiogenesis in zebrafish
por: Koltowska, Katarzyna, et al.
Publicado: (2015)

A Novel Splice-Site Mutation in VEGFC Is Associated with Congenital Primary Lymphoedema of Gordon
por: Nadarajah, Noeline, et al.
Publicado: (2018)

Yap1 promotes sprouting and proliferation of lymphatic progenitors downstream of Vegfc in the zebrafish trunk
por: Grimm, Lin, et al.
Publicado: (2019)

Exosome engineering in cell therapy and drug delivery
por: Sadeghi, Somaye, et al.
Publicado: (2023)

The parallel growth of motoneuron axons with the dorsal aorta depends on Vegfc/Vegfr3 signaling in zebrafish
por: Kwon, Hyouk-Bum, et al.
Publicado: (2013)

Vegfc/d-dependent regulation of the lymphatic vasculature during cardiac regeneration is influenced by injury context
por: Vivien, Céline J., et al.
Publicado: (2019)

Vascularized lymph node transplantation successfully reverses lymphedema and maintains immunity in a rat lymphedema model
por: Sakarya, Ahmet Hamdi, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_3eh5vtfublr7u9ap3dub08m06a