Retrospective Analysis of the Relationship between Two Anthrax Outbreaks in Kazakhstan Based on Genomic Data

We present a retrospective analysis of strains from two anthrax outbreaks in western Kazakhstan in 2009. The outbreaks occurred during the same period and in the same area located close to main roads, favoring a single source of infection. However, multilocus variable-number tandem-repeat analysis (...

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Detalles Bibliográficos
Autores principales: Shevtsov, Alexandr, Vergnaud, Gilles, Amirgazin, Asylulan, Lukhnova, Larissa, Izbanova, Uinkul, Shevtsov, Vladislav, Ramankulov, Yerlan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Genome Sequences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7729412/
https://www.ncbi.nlm.nih.gov/pubmed/33303664
http://dx.doi.org/10.1128/MRA.01126-20
Descripción
Sumario:We present a retrospective analysis of strains from two anthrax outbreaks in western Kazakhstan in 2009. The outbreaks occurred during the same period and in the same area located close to main roads, favoring a single source of infection. However, multilocus variable-number tandem-repeat analysis (MLVA), canonical single-nucleotide polymorphism (CanSNP) analysis, and genome-wide analysis demonstrated that the outbreaks were not connected.

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