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Strand Displacement Activity of PrimPol
Human PrimPol is a unique enzyme possessing DNA/RNA primase and DNA polymerase activities. In this work, we demonstrated that PrimPol efficiently fills a 5-nt gap and possesses the conditional strand displacement activity stimulated by Mn(2+) ions and accessory replicative proteins RPA and PolDIP2....
Autores principales: | Boldinova, Elizaveta O., Belousova, Ekaterina A., Gagarinskaya, Diana I., Maltseva, Ekaterina A., Khodyreva, Svetlana N., Lavrik, Olga I., Makarova, Alena V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7729601/ https://www.ncbi.nlm.nih.gov/pubmed/33261049 http://dx.doi.org/10.3390/ijms21239027 |
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