Downregulation of miR-506-3p Facilitates EGFR-TKI Resistance through Induction of Sonic Hedgehog Signaling in Non-Small-Cell Lung Cancer Cell Lines

Non-small-cell lung cancer (NSCLC) patients with epidermal growth factor receptor (EGFR) mutation eventually develop resistance to EGFR-targeted tyrosine kinase inhibitors (TKIs). Treatment resistance remains the primary obstacle to the successful treatment of NSCLC. Although drug resistance mechani...

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Detalles Bibliográficos
Autores principales: Haque, Inamul, Kawsar, Hameem I., Motes, Hannah, Sharma, Mukut, Banerjee, Snigdha, Banerjee, Sushanta K., Godwin, Andrew K., Huang, Chao H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7729622/
https://www.ncbi.nlm.nih.gov/pubmed/33291316
http://dx.doi.org/10.3390/ijms21239307

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