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Bacterial Biofilm Formation Using PCL/Curcumin Electrospun Fibers and Its Potential Use for Biotechnological Applications
Electrospun nanofibers are used for many applications due to their large surface area, mechanical properties, and bioactivity. Bacterial biofilms are the cause of numerous problems in biomedical devices and in the food industry. On the other hand, these bacterial biofilms can produce interesting met...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7729789/ https://www.ncbi.nlm.nih.gov/pubmed/33291216 http://dx.doi.org/10.3390/ma13235556 |
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author | Pompa-Monroy, Daniella Alejandra Figueroa-Marchant, Paulina Guadalupe Dastager, Syed G. Thorat, Meghana Namdeo Iglesias, Ana Leticia Miranda-Soto, Valentín Pérez-González, Graciela Lizeth Villarreal-Gómez, Luis Jesús |
author_facet | Pompa-Monroy, Daniella Alejandra Figueroa-Marchant, Paulina Guadalupe Dastager, Syed G. Thorat, Meghana Namdeo Iglesias, Ana Leticia Miranda-Soto, Valentín Pérez-González, Graciela Lizeth Villarreal-Gómez, Luis Jesús |
author_sort | Pompa-Monroy, Daniella Alejandra |
collection | PubMed |
description | Electrospun nanofibers are used for many applications due to their large surface area, mechanical properties, and bioactivity. Bacterial biofilms are the cause of numerous problems in biomedical devices and in the food industry. On the other hand, these bacterial biofilms can produce interesting metabolites. Hence, the objective of this study is to evaluate the efficiency of poly (Ɛ- caprolactone)/Curcumin (PCL/CUR) nanofibers to promote bacterial biofilm formation. These scaffolds were characterized by scanning electron microscopy (SEM), which showed homogeneous fibers with diameters between 441–557 nm; thermogravimetric analysis and differential scanning calorimetry (TGA and DSC) demonstrated high temperature resilience with degradation temperatures over >350 °C; FTIR and (1)H-NMR serve as evidence of CUR incorporation in the PCL fibers. PCL/CUR scaffolds successfully promoted the formation of Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa biofilms. These results will be valuable in the study of controlled harvesting of pathogenic biofilms as well as in metabolites production for biotechnological purposes. |
format | Online Article Text |
id | pubmed-7729789 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-77297892020-12-12 Bacterial Biofilm Formation Using PCL/Curcumin Electrospun Fibers and Its Potential Use for Biotechnological Applications Pompa-Monroy, Daniella Alejandra Figueroa-Marchant, Paulina Guadalupe Dastager, Syed G. Thorat, Meghana Namdeo Iglesias, Ana Leticia Miranda-Soto, Valentín Pérez-González, Graciela Lizeth Villarreal-Gómez, Luis Jesús Materials (Basel) Article Electrospun nanofibers are used for many applications due to their large surface area, mechanical properties, and bioactivity. Bacterial biofilms are the cause of numerous problems in biomedical devices and in the food industry. On the other hand, these bacterial biofilms can produce interesting metabolites. Hence, the objective of this study is to evaluate the efficiency of poly (Ɛ- caprolactone)/Curcumin (PCL/CUR) nanofibers to promote bacterial biofilm formation. These scaffolds were characterized by scanning electron microscopy (SEM), which showed homogeneous fibers with diameters between 441–557 nm; thermogravimetric analysis and differential scanning calorimetry (TGA and DSC) demonstrated high temperature resilience with degradation temperatures over >350 °C; FTIR and (1)H-NMR serve as evidence of CUR incorporation in the PCL fibers. PCL/CUR scaffolds successfully promoted the formation of Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa biofilms. These results will be valuable in the study of controlled harvesting of pathogenic biofilms as well as in metabolites production for biotechnological purposes. MDPI 2020-12-06 /pmc/articles/PMC7729789/ /pubmed/33291216 http://dx.doi.org/10.3390/ma13235556 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Pompa-Monroy, Daniella Alejandra Figueroa-Marchant, Paulina Guadalupe Dastager, Syed G. Thorat, Meghana Namdeo Iglesias, Ana Leticia Miranda-Soto, Valentín Pérez-González, Graciela Lizeth Villarreal-Gómez, Luis Jesús Bacterial Biofilm Formation Using PCL/Curcumin Electrospun Fibers and Its Potential Use for Biotechnological Applications |
title | Bacterial Biofilm Formation Using PCL/Curcumin Electrospun Fibers and Its Potential Use for Biotechnological Applications |
title_full | Bacterial Biofilm Formation Using PCL/Curcumin Electrospun Fibers and Its Potential Use for Biotechnological Applications |
title_fullStr | Bacterial Biofilm Formation Using PCL/Curcumin Electrospun Fibers and Its Potential Use for Biotechnological Applications |
title_full_unstemmed | Bacterial Biofilm Formation Using PCL/Curcumin Electrospun Fibers and Its Potential Use for Biotechnological Applications |
title_short | Bacterial Biofilm Formation Using PCL/Curcumin Electrospun Fibers and Its Potential Use for Biotechnological Applications |
title_sort | bacterial biofilm formation using pcl/curcumin electrospun fibers and its potential use for biotechnological applications |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7729789/ https://www.ncbi.nlm.nih.gov/pubmed/33291216 http://dx.doi.org/10.3390/ma13235556 |
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