Cargando…

Iodine status during pregnancy and at 6 weeks, 6, 12 and 18 months post‐partum

Iodine deficiency during pregnancy and in the post‐partum period may lead to impaired child development. Our aim is to describe iodine status longitudinally in women from pregnancy until 18 months post‐partum. Furthermore, we explore whether iodine status is associated with dietary intake, iodine‐co...

Descripción completa

Detalles Bibliográficos
Autores principales: Aakre, Inger, Morseth, Marianne Sandsmark, Dahl, Lisbeth, Henjum, Sigrun, Kjellevold, Marian, Moe, Vibeke, Smith, Lars, Markhus, Maria Wik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7729798/
https://www.ncbi.nlm.nih.gov/pubmed/32602197
http://dx.doi.org/10.1111/mcn.13050
_version_ 1783621540851482624
author Aakre, Inger
Morseth, Marianne Sandsmark
Dahl, Lisbeth
Henjum, Sigrun
Kjellevold, Marian
Moe, Vibeke
Smith, Lars
Markhus, Maria Wik
author_facet Aakre, Inger
Morseth, Marianne Sandsmark
Dahl, Lisbeth
Henjum, Sigrun
Kjellevold, Marian
Moe, Vibeke
Smith, Lars
Markhus, Maria Wik
author_sort Aakre, Inger
collection PubMed
description Iodine deficiency during pregnancy and in the post‐partum period may lead to impaired child development. Our aim is to describe iodine status longitudinally in women from pregnancy until 18 months post‐partum. Furthermore, we explore whether iodine status is associated with dietary intake, iodine‐containing supplement use and breastfeeding status from pregnancy until 18 months post‐partum. We also assess the correlation between maternal iodine status 18 months post‐partum and child iodine status at 18 months of age. Iodine status was measured by urinary iodine concentration (UIC) during pregnancy (n = 1,004), 6 weeks post‐partum (n = 915), 6 months post‐partum (n = 849), 12 months post‐partum (n = 733) and 18 months post‐partum (n = 714). The toddlers' UIC was assessed at 18 months of age (n = 416). Demographic variables and dietary data (food frequency questionnaire) were collected during pregnancy, and dietary data and breastfeeding practices were collected at all time points post‐partum. We found that iodine status was insufficient in both pregnant and post‐partum women. The UIC was at its lowermost 6 weeks post‐partum and gradually improved with increasing time post‐partum. Intake of milk and use of iodine‐containing supplements significantly increased the odds of having a UIC above 100 μg/L. Neither the mothers' UIC, vegetarian practice, nor exclusion of milk and dairy products were associated with the toddlers UIC 18 months post‐partum. Women who exclude milk and dairy products from their diets and/or do not use iodine‐containing supplements may be at risk of iodine deficiency. The women possibly also have an increased risk of thyroid dysfunction and for conceiving children with nonoptimal developmental status.
format Online
Article
Text
id pubmed-7729798
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-77297982020-12-13 Iodine status during pregnancy and at 6 weeks, 6, 12 and 18 months post‐partum Aakre, Inger Morseth, Marianne Sandsmark Dahl, Lisbeth Henjum, Sigrun Kjellevold, Marian Moe, Vibeke Smith, Lars Markhus, Maria Wik Matern Child Nutr Original Articles Iodine deficiency during pregnancy and in the post‐partum period may lead to impaired child development. Our aim is to describe iodine status longitudinally in women from pregnancy until 18 months post‐partum. Furthermore, we explore whether iodine status is associated with dietary intake, iodine‐containing supplement use and breastfeeding status from pregnancy until 18 months post‐partum. We also assess the correlation between maternal iodine status 18 months post‐partum and child iodine status at 18 months of age. Iodine status was measured by urinary iodine concentration (UIC) during pregnancy (n = 1,004), 6 weeks post‐partum (n = 915), 6 months post‐partum (n = 849), 12 months post‐partum (n = 733) and 18 months post‐partum (n = 714). The toddlers' UIC was assessed at 18 months of age (n = 416). Demographic variables and dietary data (food frequency questionnaire) were collected during pregnancy, and dietary data and breastfeeding practices were collected at all time points post‐partum. We found that iodine status was insufficient in both pregnant and post‐partum women. The UIC was at its lowermost 6 weeks post‐partum and gradually improved with increasing time post‐partum. Intake of milk and use of iodine‐containing supplements significantly increased the odds of having a UIC above 100 μg/L. Neither the mothers' UIC, vegetarian practice, nor exclusion of milk and dairy products were associated with the toddlers UIC 18 months post‐partum. Women who exclude milk and dairy products from their diets and/or do not use iodine‐containing supplements may be at risk of iodine deficiency. The women possibly also have an increased risk of thyroid dysfunction and for conceiving children with nonoptimal developmental status. John Wiley and Sons Inc. 2020-06-29 /pmc/articles/PMC7729798/ /pubmed/32602197 http://dx.doi.org/10.1111/mcn.13050 Text en © 2020 The Authors. Maternal & Child Nutrition published by John Wiley & Sons, Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Aakre, Inger
Morseth, Marianne Sandsmark
Dahl, Lisbeth
Henjum, Sigrun
Kjellevold, Marian
Moe, Vibeke
Smith, Lars
Markhus, Maria Wik
Iodine status during pregnancy and at 6 weeks, 6, 12 and 18 months post‐partum
title Iodine status during pregnancy and at 6 weeks, 6, 12 and 18 months post‐partum
title_full Iodine status during pregnancy and at 6 weeks, 6, 12 and 18 months post‐partum
title_fullStr Iodine status during pregnancy and at 6 weeks, 6, 12 and 18 months post‐partum
title_full_unstemmed Iodine status during pregnancy and at 6 weeks, 6, 12 and 18 months post‐partum
title_short Iodine status during pregnancy and at 6 weeks, 6, 12 and 18 months post‐partum
title_sort iodine status during pregnancy and at 6 weeks, 6, 12 and 18 months post‐partum
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7729798/
https://www.ncbi.nlm.nih.gov/pubmed/32602197
http://dx.doi.org/10.1111/mcn.13050
work_keys_str_mv AT aakreinger iodinestatusduringpregnancyandat6weeks612and18monthspostpartum
AT morsethmariannesandsmark iodinestatusduringpregnancyandat6weeks612and18monthspostpartum
AT dahllisbeth iodinestatusduringpregnancyandat6weeks612and18monthspostpartum
AT henjumsigrun iodinestatusduringpregnancyandat6weeks612and18monthspostpartum
AT kjellevoldmarian iodinestatusduringpregnancyandat6weeks612and18monthspostpartum
AT moevibeke iodinestatusduringpregnancyandat6weeks612and18monthspostpartum
AT smithlars iodinestatusduringpregnancyandat6weeks612and18monthspostpartum
AT markhusmariawik iodinestatusduringpregnancyandat6weeks612and18monthspostpartum