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Neural Stem Cell-Derived Exosomes Revert HFD-Dependent Memory Impairment via CREB-BDNF Signalling
Overnutrition and metabolic disorders impair cognitive functions through molecular mechanisms still poorly understood. In mice fed with a high fat diet (HFD) we analysed the expression of synaptic plasticity-related genes and the activation of cAMP response element-binding protein (CREB)-brain-deriv...
Autores principales: | Spinelli, Matteo, Natale, Francesca, Rinaudo, Marco, Leone, Lucia, Mezzogori, Daniele, Fusco, Salvatore, Grassi, Claudio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7729830/ https://www.ncbi.nlm.nih.gov/pubmed/33256199 http://dx.doi.org/10.3390/ijms21238994 |
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