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Leptin Mediated Pathways Stabilize Posttraumatic Insulin and Osteocalcin Patterns after Long Bone Fracture and Concomitant Traumatic Brain Injury and Thus Influence Fracture Healing in a Combined Murine Trauma Model
Recent studies on insulin, leptin, osteocalcin (OCN), and bone remodeling have evoked interest in the interdependence of bone formation and energy household. Accordingly, this study attempts to investigate trauma specific hormone changes in a murine trauma model and its influence on fracture healing...
Autores principales: | Garbe, Anja, Graef, Frank, Appelt, Jessika, Schmidt-Bleek, Katharina, Jahn, Denise, Lünnemann, Tim, Tsitsilonis, Serafeim, Seemann, Ricarda |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7729898/ https://www.ncbi.nlm.nih.gov/pubmed/33266324 http://dx.doi.org/10.3390/ijms21239144 |
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