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Selective hepatitis B and D virus entry inhibitors from the group of pentacyclic lupane-type betulin-derived triterpenoids

Current treatment options against hepatitis B and D virus (HBV/HDV) infections have only limited curative effects. Identification of Na(+)/taurocholate co-transporting polypeptide (NTCP) as the high-affinity hepatic receptor for both viruses in 2012 enables target-based development of HBV/HDV cell-e...

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Detalles Bibliográficos
Autores principales:	Kirstgen, Michael, Lowjaga, Kira Alessandra Alicia Theresa, Müller, Simon Franz, Goldmann, Nora, Lehmann, Felix, Alakurtti, Sami, Yli-Kauhaluoma, Jari, Glebe, Dieter, Geyer, Joachim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7729925/ https://www.ncbi.nlm.nih.gov/pubmed/33303817 http://dx.doi.org/10.1038/s41598-020-78618-2

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