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Activity-Based Protein Profiling Reveals Potential Dasatinib Targets in Gastric Cancer

Dasatinib is a multi-target kinase inhibitor, whose targets include BCR-ABL, SRC family kinases, and various cancer kinases. The elevated SRC activity in gastric cancer (GC) has prompted the need for the therapeutic application of dasatinib in GC. We observed that the efficacy of dasatinib varied wi...

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Detalles Bibliográficos
Autores principales: Choi, Kyoung-Min, Cho, Eunji, Bang, Geul, Lee, Seong-Jae, Kim, Boram, Kim, Ji-Hee, Park, Seo-Gyu, Han, Eun Hee, Chung, Young-Ho, Kim, Jin Young, Kim, Eunjung, Kim, Jae-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7729964/
https://www.ncbi.nlm.nih.gov/pubmed/33291786
http://dx.doi.org/10.3390/ijms21239276