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A protein of the metallo-hydrolase/oxidoreductase superfamily with both beta-lactamase and ribonuclease activity is linked with translation in giant viruses
Proteins with a metallo-beta-lactamase (MBL) fold have been largely studied in bacteria in the framework of resistance to beta-lactams, but their spectrum of activities is broader. We show here that the giant Tupanvirus also encodes a MBL fold-protein that has orthologs in other giant viruses, a dee...
Autores principales: | Colson, Philippe, Pinault, Lucile, Azza, Said, Armstrong, Nicholas, Chabriere, Eric, La Scola, Bernard, Pontarotti, Pierre, Raoult, Didier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7729979/ https://www.ncbi.nlm.nih.gov/pubmed/33303919 http://dx.doi.org/10.1038/s41598-020-78658-8 |
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