Cargando…

Synthesis, Characterization, and Antiproliferative Activity of Novel Chiral [QuinoxP*AuCl(2)](+) Complexes

Herein is reported the synthesis of two Au(III) complexes bearing the (R,R)-(–)-2,3-Bis(tert-butylmethylphosphino)quinoxaline (R,R-QuinoxP*) or (S,S)-(+)-2,3-Bis(tert-butylmethylphosphino)quinoxaline (S,S-QuinoxP*) ligands. By reacting two stoichiometric equivalents of HAuCl(4).3H(2)O to one equival...

Descripción completa

Detalles Bibliográficos
Autores principales:	Arojojoye, Adedamola S., Mertens, R. Tyler, Ofori, Samuel, Parkin, Sean R., Awuah, Samuel G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730091/ https://www.ncbi.nlm.nih.gov/pubmed/33291802 http://dx.doi.org/10.3390/molecules25235735

Ejemplares similares

Aurophilic Molecules on Surfaces. Part II. (NapNC)AuCl on Au(111)
por: Wagner, Thorsten, et al.
Publicado: (2023)

Aurophilic Molecules on Surfaces. Part I. (NapNC)AuCl on Au(110)
por: Györök, Michael, et al.
Publicado: (2023)

AuCl(3)-Catalyzed Hemiacetal Activation for the Stereoselective Synthesis of 2-Deoxy Trehalose Derivatives
por: Jeanneret, Robin, et al.
Publicado: (2022)

Effect of Au nano-particle aggregation on the deactivation of the AuCl(3)/AC catalyst for acetylene hydrochlorination
por: Dai, Bin, et al.
Publicado: (2015)

Closed-shell d(10)–d(10) in [AuCl(CNR)](n) and [AuCl(CO)](n) (n = 1, 2; R = –H, –CH(3), –Cy) complexes: quantum chemistry study of their electronic and optical properties
por: Mendizabal, Fernando, et al.
Publicado: (2022)

Single-Crystal-to-Single-Crystal Anion Exchange in a Gadolinium MOF: Incorporation of POMs and [AuCl(4)](−)
por: López-Cabrelles, Javier, et al.
Publicado: (2016)

Synthetic Control of Mitochondrial Dynamics: Developing Three-Coordinate Au(I) Probes for Perturbation of Mitochondria Structure and Function
por: Mertens, R. Tyler, et al.
Publicado: (2021)

Genome wide transcriptome analysis reveals ABA mediated response in Arabidopsis during gold (AuCl(−)(4)) treatment
por: Shukla, Devesh, et al.
Publicado: (2014)

Molecular Recognition of Metal Complexes by DNA: A Comparative Study of the Interactions of the Parent Complexes [PtCl(TERPY)]Cl and [AuCl(TERPY)]Cl (2) with Double Stranded DNA
por: Messori, Luigi, et al.
Publicado: (2005)

Synthesis and crystal structure of 1,3-bis(4-hydroxyphenyl)-1H-imidazol-3-ium chloride
por: Mertens, R. Tyler, et al.
Publicado: (2019)

Gold(I/III)-Phosphine Complexes as Potent Antiproliferative Agents
por: Kim, Jong Hyun, et al.
Publicado: (2019)

Synthesis and characterization of d (5)‐barbarin for use in barbarin‐related research
por: Kudrimoti, Sucheta, et al.
Publicado: (2022)

6,7-Dichloro-2,3-bis(pyridin-2-yl)quinoxaline
por: Crundwell, Guy, et al.
Publicado: (2015)

Mild deprotection of the N-tert-butyloxycarbonyl (N-Boc) group using oxalyl chloride
por: George, Nathaniel, et al.
Publicado: (2020)

Correction: Mild deprotection of the N-tert-butyloxycarbonyl (N-Boc) group using oxalyl chloride
por: George, Nathaniel, et al.
Publicado: (2021)

Cancer cell-selective modulation of mitochondrial respiration and metabolism by potent organogold(iii) dithiocarbamates
por: Mertens, Randall T., et al.
Publicado: (2020)

An anti-glioblastoma gold(i)–NHC complex distorts mitochondrial morphology and bioenergetics to induce tumor growth inhibition
por: Greif, Charles E., et al.
Publicado: (2023)

Genome-wide CRISPR Screen Reveal Targets of Chiral Gold(I) Anticancer Compound in Mammalian Cells
por: Kim, Jong Hyun, et al.
Publicado: (2022)

Anticancer gold(iii)-bisphosphine complex alters the mitochondrial electron transport chain to induce in vivo tumor inhibition
por: Kim, Jong Hyun, et al.
Publicado: (2021)

Small-Molecule Poly(ADP-ribose) Polymerase and PD-L1 Inhibitor Conjugates as Dual-Action Anticancer Agents
por: Ofori, Samuel, et al.
Publicado: (2019)

Gold(III)-P-chirogenic complex induces mitochondrial dysfunction in triple-negative breast cancer
por: Olelewe, Chibuzor, et al.
Publicado: (2022)

Synthesis of axially chiral oxazoline–carbene ligands with an N-naphthyl framework and a study of their coordination with AuCl·SMe(2)
por: Wang, Feijun, et al.
Publicado: (2012)

Binding of [Au(dien)Cl]Cl(2) to Tripeptides
por: Best, Sabine L., et al.
Publicado: (1994)

Evaluation of genotoxic and oxidative stress potential of Ajakanga Landfill Leachate in rats
por: Arojojoye, Oluwatosin A., et al.
Publicado: (2022)

Syntheses of tetrahydroquinoline-based chiral carbene precursors and the related chiral NHC–Au(i) complex
por: Zhan, Licheng, et al.
Publicado: (2020)

Predicting the bioactivity of 2-alkoxycarbonylallyl esters as potential antiproliferative agents against pancreatic cancer (MiaPaCa-2) cell lines: GFA-based QSAR and ELM-based models with molecular docking
por: Oyeneyin, Oluwatoba Emmanuel, et al.
Publicado: (2021)

Enzymatic Synthesis of 2-Chloropurine Arabinonucleosides with Chiral Amino Acid Amides at the C6 Position and an Evaluation of Antiproliferative Activity In Vitro
por: Eletskaya, Barbara Z., et al.
Publicado: (2023)

Structurally Similar Triphenylphosphine-Stabilized Undecagolds, Au(11)(PPh(3))(7)Cl(3) and [Au(11)(PPh(3))(8)Cl(2)]Cl, Exhibit Distinct Ligand Exchange Pathways with Glutathione
por: McKenzie, Lallie C., et al.
Publicado: (2014)

Antiproliferative Activity of Functionalized Histidine‐derived Au(I) bis‐NHC Complexes for Bioconjugation
por: Jakob, Christian H. G., et al.
Publicado: (2020)

[AU(DIEN)Cl]Cl(2): Exchange Phenomena Observed by (1)H and (13)C NMR Spectroscopy
por: Best, Sabine L., et al.
Publicado: (1999)

Histological Changes in Kidney and Liver of Rats Due to Gold (III) Compound [Au(en)Cl(2)]Cl
por: Ahmed, Ayesha, et al.
Publicado: (2012)

Synthesis and enantioseparation of chiral Au(13) nanoclusters protected by bis-N-heterocyclic carbene ligands
por: Yi, Hong, et al.
Publicado: (2021)

Au(I)Cl-bound N-heterocyclic carbene ligands form MII4(LAuCl)(6) integrally gilded cages
por: Ramsay, William J., et al.
Publicado: (2015)

Association between endothelial nitric oxide synthase (eNOS) gene variants and nitric oxide production in preeclampsia: a case–control study in Ghana
por: Fondjo, Linda Ahenkorah, et al.
Publicado: (2023)

Chiral Imidazolium-Functionalized Au Nanoparticles: Reversible Aggregation and Molecular Recognition
por: Lomelí-Rosales, Diego Alberto, et al.
Publicado: (2016)

Long‐Range Chirality Recognition of a Polar Molecule on Au(111)
por: Kong, Huihui, et al.
Publicado: (2019)

Comparing Metal–Halide and −Oxygen Adducts in Oxidative C/O–H Activation: Au(III)–Cl versus Au(III)–OH
por: Lovisari, Marta, et al.
Publicado: (2021)

Tuning HAuCl(4)/Sodium Citrate Stoichiometry to Fabricate Chitosan-Au Nanocomposites
por: Torres-Ferrer, Luis R., et al.
Publicado: (2022)

Chiral symmetry breaking yields the I-Au(60) perfect golden shell of singular rigidity
por: Mullins, S.-M., et al.
Publicado: (2018)

The anti-breast cancer stem cell properties of gold(i)-non-steroidal anti-inflammatory drug complexes
por: Johnson, Alice, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ti2olj28v0mqdj26d9o1psivmg